Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
Oral administration of zein-based nanoparticles reduces glycemia and improves glucose tolerance in…
The aim was to evaluate the effect of zein-based nanoparticles on the glucose homeostasis, following oral administration to Wistar rats. For this purpose, bare nanoparticles (NP, with tropism for the upper intestinal regions) and poly(ethylene glycol)-coated nanoparticles (NP-PEG), with the…
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New and Novel Excipients – Part 2
A week ago I wrote about the importance of new and novel excipients for the pharmaceutical industry and presented Klucel™ xtend and BioSustane™ in last week´s edition of "The Excipients Week".
In the meantime I launched a small poll with the title "Was there innovation in excipients over the last…
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Formulation and characterization of orodispersible tablet of glimepiride
Abstract
The present study is regarding, Glimepiride is one derivatives of sulfonyl urea used in the treatment of Type II DM which classified as class-II (BCS) of high permeability and low degree of solubility. The endeavor is to improve its solubility by solvent vaporization method to enhance…
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Existing and emerging mitigation strategies for the prevention of accidental overdose from oral…
Misadventure with pharmaceutical oral medication has been on the rise, with the opioid crisis playing a major part. Drug overdose related to opioids has become such an issue, that it has been labelled a worldwide crisis. This review explores the mitigation strategies currently in place to prevent…
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RXCIPIENTS® FM 1000 – A versatile excipient for orally disintegrating tablet (ODT)…
1. Introduction
Certain patient groups, specifically elderly and infant
patients, experience difficulties with swallowing oral
dosages of medication. Orally disintegrating tablets (ODTs) are one approach to ease the intake, helping patients to comply with their prescription plans.
A…
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Progress in oral insulin delivery by PLGA nanoparticles for the management of diabetes
Currently, the only practical way to treat type 1 and advanced insulin-dependent type 2 diabetes mellitus (T1/2DM) is the frequent subcutaneous injection of insulin, which is significantly different physiologically from endogenous insulin secretion from pancreatic islets and can lead to…
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When coating runs smoothly – Parteck® COAT: Reduce your process time with an optimized polymer…
Our broad range of formulation products covers excipients for solid, semi-solid and liquid dosage forms for small and large molecules. Additionally, we offer a portfolio of drug delivery compounds (DDCs), as well as solutions for solubility enhancement and controlled release. Benefit from our…
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Design and development of orally disintegrating films: A platform based on hydroxypropyl…
From a design of experiments (DOE) performed under four independent variables, with the filmogenicity conditions and shortest disintegration time as the answers, a new oral disintegrating film (ODF) based on hydroxypropyl methylcellulose (HPMC) and guar gum (GG) with the essential oil of …
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Pharmaceutical Technical Newsletter F-Melt® by Fuji Chemical Industries
See the second issue of Fuji Chemical Industries Technical Newsletter. This issue focuses on achieving higher tablet hardness with pleasant mouth feel at good oral disintegranting (OD) times by addition of other common excipients.
F-Melt® fast melt tablet made easy!
NEWSLETTER HIGHLIGHT…
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FlowLac® – MEGGLE’s spray-dried lactose grades for direct compression
FlowLac by MEGGLE is directly compressible lactose having a spherical agglomerate shape, consisting of small alpha-lactose monohydrate crystals bound by amorphous lactose. It is produced by spray-drying a suspension of fine milled alpha-lactose monohydrate crystals in a solution of lactose. When…
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