Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
What’s next in the use of opacifiers for cosmetic coatings of solid dosage forms? Insights on…
The consolidated use of coatings containing E171 (i.e. titanium dioxide, TiO2) as an opacifier has made the white color of the resulting dosage forms a quality standard in the pharmaceutical and dietary supplement fields. This color is also associated with the efficiency of the coating layer in…
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3D printing of pharmaceutical oral solid dosage forms by fused deposition: the enhancement of…
3D printing (3DP) by fused deposition modelling (FDM) is one of the most extensively developed methods in additive manufacturing. Optimizing printability by improving feedability, nozzle extrusion, and layer deposition is crucial for manufacturing solid oral dosage forms with desirable properties.…
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Dose-independent Drug Release from 3D Printed Oral Medicines for Patient-specific Dosing to Improve…
Fused deposition modelling (FDM) 3D printing provides the ability to address individual patients’ therapeutic needs without having to change the formulation every time. This is particularly interesting for dosing and release modelling. In this study, a geometry model was developed that can represent…
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Use of Two-Factor Dispersion Analysis for Studying the Pharmaceutical and Technological Properties…
The influence of the type and ratio of co-process fillers and lubricating excipients on the properties of the final dosage form was studied during the development of the composition and technology for GK-2 tablets dispersed in the oral cavity.
The pharmaceutical and technological properties,…
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Concept of Orodispersible or Mucoadhesive “Tandem Films” and Their Pharmaceutical Realization
Orodispersible or mucoadhesive films as a patient-oriented dosage form for low-dosed drugs are usually produced using solvent casting. This paper presents a modification of the solvent casting technique that aimed to divide oral films into two or more compartments.
The proposed objectives and…
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Impact of Vertical Blender Unit Parameters on Subsequent Process Parameters and Tablet Properties in…
The continuous manufacturing of solid oral-dosage forms represents an emerging technology among the pharmaceutical industry, where several process steps are combined in one production line. As all mixture components, including the lubricant (magnesium stearate), are passing simultaneously through…
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Drug delivery to the intestinal lymph by oral formulations
Oral drug delivery systems (DDS) targeting lymphocytes in intestinal lymphatic vessels, ducts, and nodes are useful for treating diverse diseases. The intestinal lymph harbors numerous lymphocyte subsets, and DDS containing lipids such as triglycerides and fatty acids can deliver drugs to the lymph…
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100% visual inspection of tablets produced with continuous direct compression and coating
Visual appearance of tablets is an important property for patients. Since the visual appearance is most strongly influenced by the applied coating, this necessitates a high level of process control and homogeneity in the coating process. In recent years, a number of tablet coaters have been…
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Real-Time Monitoring of Powder Mass Flowrates for Plant-Wide Control of a Continuous Direct…
While measurement and monitoring of powder/particulate mass flow rate are not essential to the execution of traditional batch pharmaceutical tablet manufacturing, in continuous operation, it is an important additional critical process parameter. It has a key role both in establishing that the…
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Towards Virtual Bioequivalence Studies for Oral Dosage Forms Containing Poorly Water-Soluble Drugs:…
The objective of the present study was to develop a physiologically based biopharmaceutics (PBBM) approach to predict the bioequivalence of dosage forms containing poorly soluble drugs. Aripiprazole and enzalutamide were used as model drugs. Variations in the gastrointestinal (GI) physiological…
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