Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
Better and greener: sustainable pharmaceutical manufacturing technologies for highly bioavailable…
In the last decades, Green Chemistry has been gaining widespread attention within the pharmaceutical field. It is thus very important to bring more sustainable approaches into the design and manufacture of effective oral drug delivery systems.
This review focuses on spray congealing and…
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Performance Evaluation of Montelukast Pediatric Formulations: Part II — a PBPK Modelling Approach
This study aimed to build a physiologically based pharmacokinetic (PBPK) model coupled with age-appropriate in vitro dissolution data to describe drug performance in adults and pediatric patients. Montelukast sodium was chosen as a model drug. Two case studies were investigated: case study 1 focused…
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Review of paediatric gastrointestinal physiology relevant to the absorption of orally administered…
Despite much progress in regulations to improve paediatric drug development, there remains a significant need to develop better medications for children. For the design of oral dosage forms, a detailed understanding of the specific gastrointestinal (GI) conditions in children of different age…
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Oral administration of buparvaquone nanostructured lipid carrier enables in vivo activity against…
Leishmaniasis, a neglected tropical disease, is prevalent in 98 countries with the occurrence of 1.3 million new cases annually. The conventional therapy for visceral leishmaniasis requires hospitalization due to the severe adverse effects of the drugs, which are administered parenterally.…
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Breaking patterns of press-coated tablets during the diametral compression test: Influence of the…
Press-coated tablets are a high-interest technology in chronopharmaceutics, for modified release applications. As for any kind of tablet, the test of the mechanical resistance is of primary importance at the industrial level during both the development and production steps. For this purpose, the…
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Machine Learning and Machine Vision Accelerate 3D Printed Orodispersible Film Development
Orodispersible films (ODFs) are an attractive delivery system for a myriad of clinical applications and possess both large economical and clinical rewards. However, the manufacturing of ODFs does not adhere to contemporary paradigms of personalised, on-demand medicine, nor sustainable manufacturing.…
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Investigating the Role of Excipients on the Physical Stability of Directly Compressed Tablets
Stability studies are an integral part of the drug development process for any drug product. In addition to monitoring chemical degradation, the physical stability of a drug product must also be evaluated to ensure that the drug release and performance is not affected by storage. In this study,…
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On-demand webinar: 3D printing of tablets – A new era of pharmaceutical manufacturing
Additive manufacturing is gaining increasing attention in the field of pharmaceutical manufacturing. Evaluations are mainly driven by advances in individualized therapy and fast track development of clinical trial material. Melt based systems provide the additional advantage of enhancing the…
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Application of Reverse Engineering in the Field of Pharmaceutical Tablets Using Raman Mapping and…
Raman micro-spectroscopy technique offers a combination of relatively high spatial resolution with identification of components or mixtures of components in different sample areas, e.g. on the surface or the cross-section of a sample. This study is focused on the analysis of the tablets from…
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European Paediatric Formulary: two draft texts released for public consultation
The European Directorate for the Quality of Medicines & HealthCare (EDQM) has just released Issue 4 of Pharmeuropa PaedForm, which contains two texts for public consultation, Simple syrup (preservative-free) and Phosphate 60 mg/mL Oral solution, prior to their inclusion in the European…
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