Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
Gelucire® 59/14, solid surfactant for oral bioavailability enhancement
Gattefossé widens its range of functional excipients for oral bioavailability enhancement with a new grade of Gelucire®: Gelucire® 59/14, a mixture of lauroyl PEG-32 glycerides EP/NF and PEG 6000 EP/NF.
Gelucire® 59/14 is a self-emulsifying excipient used for oral bioavailability enhancement of…
Read More...
Read More...
Simultaneous determination of third-generation synthetic cannabinoids in oral fluids using…
A microporous material made of cyclodextrin units covalently immobilized into a silica network has found an innovative bioanalytical application in the sample clean-up and simultaneous isolation of three synthetic cannabinoids (ADB-CHMICA, MMB-CHMICA, and MDMB-CHMCZCA) from human oral fluid through…
Read More...
Read More...
Boost your drug bioavailability with Labrafac™ MC60
Gattefossé widens its range of high quality, functional excipients for oral bioavailability enhancement with Labrafac™ MC60, glycerol monocaprylocaprate. Labrafac™ MC60 is used for oral bioavailability enhancement of poorly water-soluble, poorly permeable drugs.
Glycerol monocaprylocaprate is a…
Read More...
Read More...
Investigating the Critical Variables of Azithromycin Oral Absorption Using In Vitro Tests and PBPK…
Azithromycin is an antibiotic listed in the essential list of medicines for adults and pediatrics. Conflicting evidence has been found regarding azithromycin classification according to the Biopharmaceutics classification system (BCS). The purpose of this study was to identify the critical variables…
Read More...
Read More...
In-vitro and in-vivo evaluation of taste-masked ibuprofen formulated in oral dry emulsions
Objective
The aim of this study was to develop a paediatric oral preparation for ibuprofen.
Significance
Ibuprofen is widely used for defervescence in children, but medication compliance is poor due to its bitter taste. Dry emulsions possess good stability and can be transported and stored…
Read More...
Read More...
An oral lipidic native testosterone formulation that is absorbed independent of food
Context
There is no licensed oral native testosterone (NT) because of challenges in the formulation. Licensed oral formulations of the ester, testosterone undecanoate (TU), require a meal for absorption and generate supraphysiological dihydrotestosterone (DHT) levels.
Objective
To develop…
Read More...
Read More...
Preparation and Evaluation of Self-emulsifying Drug Delivery System (SEDDS) of Cepharanthine
The aim of this article was to design a self-emulsifying drug delivery system (SEDDS) of loaded cepharanthine (CEP) to improve the oral bioavailability in rats. Based on the solubility determination and pseudo-ternary phase diagram, isopropyl palmitate (IPP) was chosen as the oil phase. Meanwhile,…
Read More...
Read More...
Emerging trends in the delivery of nanoformulated oxytocin across Blood-Brain barrier
Neurological diseases are related to the central nervous system disorders and considered as serious cases. Several drugs are used to treat neurological diseases; however, to date the main issue is to design a therapeutic model which can cross the blood–brain-barrier (BBB) easily. The delivery of …
Read More...
Read More...
Nanocarriers for oral delivery of biologics: small carriers for big payloads
Biologics have gained immense popularity in the past two decades as new and personalized medicines. Yet, the majority of the approved biologics are administered via the parenteral route (i.e., via injections).
Biologics therapy is usually costly as they require administration by a healthcare…
Read More...
Read More...
Nano Spray-Dried Drugs for Oral Administration: A Review
Spray drying is an important technology that is fast, simple, reproducible, and scalable. It has a wide application range, that is, in food, chemicals, and encapsulation of pharmaceuticals. The technology can be divided into conventional spray drying and nano spray drying. The key advantage of nano…
Read More...
Read More...