Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
Self-dispersing self-assembling systems for controlled oral delivery of gliclazide
Self-microemulsifying systems undergo self-dispersion to form microemulsion with subsequent self-assembly to form liquid crystalline (LC) and/or gel phases. These transitions modulate the release and absorption pattern of loaded drug. Accordingly, the primary objective was to evaluate these phases…
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In Vitro-In Silico Tools for Streamlined Development of Acalabrutinib Amorphous Solid Dispersion…
Amorphous solid dispersion (ASD) dosage forms can improve the oral bioavailability of poorly water-soluble drugs, enabling the commercialization of new chemical entities and improving the efficacy and patient compliance of existing drugs. However, the development of robust, high-performing ASD…
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Improved Bioavailability with Dry Powder Cannabidiol Inhalation: A Phase 1 Clinical Study
Oral cannabidiol (CBD) is approved by the Food and Drug Administration (FDA) to treat patients with Dravet and Lennox-Gastaut syndromes, and tuberous sclerosis complex. The therapeutic potential of oral CBD formulations is limited by extensive first-pass hepatic metabolism. Following oral…
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Using a material database and data fusion method to accelerate the process model development of high…
High shear wet granulation (HSWG) has been wildly used in manufacturing of oral solid dosage (OSD) forms, and process modeling is vital to understanding and controlling this complex process. In this paper, data fusion and multivariate modeling technique were applied to develop a…
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Polymers in Pharmaceutical Additive Manufacturing A Balancing Act Between Printability and Product…
Materials and manufacturing processes share a common purpose of enabling the pharmaceutical product to perform as intended. This review on the role of polymeric materials in additive manufacturing of oral dosage forms, focuses on the interface between the polymer and key stages of the additive…
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Polymers in Pharmaceutical Additive Manufacturing: A Balancing Act Between Printability and Product…
Materials and manufacturing processes share a common purpose of enabling the pharmaceutical product to perform as intended. This review on the role of polymeric materials in additive manufacturing of oral dosage forms, focuses on the interface between the polymer and key stages of the additive…
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Drug-Rich Phases Induced by Amorphous Solid Dispersion: Arbitrary or Intentional Goal in Oral Drug…
Among many methods to mitigate the solubility limitations of drug compounds, amorphous solid dispersion (ASD) is considered to be one of the most promising strategies to enhance the dissolution and bioavailability of poorly water-soluble drugs. The enhancement of ASD in the oral absorption of drugs…
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Maximizing the Oral Bioavailability of Poorly Water-Soluble Drugs Using Novel Oil-Like Materials in…
Lipid-based formulations, such as self-microemulsifying drug-delivery systems (SMEDDSs), are promising tools for the oral delivery of poorly water-soluble drugs. However, failure to maintain adequate aqueous solubility after coming into contact with gastrointestinal fluids is a major drawback.
In…
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See the overview of Parteck® Functional Excipients
When you design a solid dosage form, there are many factors to consider: the active ingredient, bioavailability enhancement, release kinetics, specific dosage, packaging, shelf life, and more.
Our Parteck® excipients were designed with the formulator’s challenges in mind and are particle…
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Self-Nano-Emulsifying Drug-Delivery Systems: From the Development to the Current Applications and…
Approximately one third of newly discovered drug molecules show insufficient water solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems (SNEDDSs) are one of the emerging strategies developed to tackle the issues associated with their oral delivery. SNEDDSs…
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