Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
Enhancing the oral bioavailability of simvastatin with silica-lipid hybrid particles: The effect of…
Silica-lipid hybrid (SLH) microparticles are a solidified lipid-based drug delivery system under investigation for their aptitude to enhance the oral bioavailability of poorly water-soluble drugs. The cholesterol-lowering agent, simvastatin (SIM), is poorly water-soluble and undergoes extensive…
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Convert oily actives (CBD oil) into flowable and compressible powder
FujiSil™ is a highly porous silica material. It allows you to convert oily actives into flowable and compressible powder. It is ideal for formulations with CBD oil.
Very high adsorption capability
Turn your oily active into a free-flowing powder
Multi-functional spherical highly porous…
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Enteric polymer-based microspheres by spray-drying for colonic delivery of Lactobacillus rhamnosus…
Antibiotics are well-known disruptive elements of the intestinal microbiota and antibiotic-associated diarrhea appeared as the most common complication related with post-antibiotic dysbiosis. Lactobacillus rhamnosus GG (LGG) strain is very effective in preventing antibiotic-associated diarrhea in…
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Compaction behavior of isomalt after roll compaction
Isomalt is a polyol derived from sucrose. Advantages of this excipient are its sweet taste, which is supposed to allow taste masking, the low glycemic and insulinemic response (Petzoldt, 1982), and the ability to be compacted directly. With regard to infantile patients, also the lack of…
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Preparation of Bilayer ODTs with Superior Interfacial Strength Using GRANFILLER-D
In recent years, multilayer tablets have drawn attention as dosage form that enable the production of combination drugs with API stability and precisely controlled dissolution rates, and many studies on such tablets have been reported. However, there are still few reports on the application of…
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A dual pH and microbiota-triggered coating (PhloralTM) for fail-safe colonic drug release
Enteric-coated dosage forms are widely used for targeting the ileo-colonic region of the gastrointestinal (GI) tract. However, accurate targeting is challenging due to intra- and inter-individual variability in intestinal paramaters such as fluid pH and transit times which occasionally lead to…
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The Role of Functional Excipients in Solid Oral Dosage Forms to Overcome Poor Drug Dissolution and…
Many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution rates in aqueous environments such as the luminal fluids of the gastrointestinal tract. The oral bioavailability of these compounds is usually very low as a result of their poor solubility properties. In order…
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Factors affecting the stability and performance of amorphous solid dispersions of poorly soluble…
Over the last twenty years, the poor solubility profile of pipeline drugs has limited their development as solid oral dosage forms. Formulating these APIs as amorphous solid dispersions is one strategy to overcome their poor aqueous solubility. The major limitation to amorphous solid dispersion…
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Review of Real-Time Release Testing of Pharmaceutical Tablets: State-of-the Art, Challenges and…
In the last decade significant advances have been made in process analytical technologies and digital manufacturing of pharmaceutical oral solid dosage forms leading to enhanced product knowledge and process understanding. These developments provide an excellent platform for realising real-time…
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Characterization and comparison of deferasirox fast disintegrating tablets prepared by direct…
The aim of this study was to develop direct compressed and lyophilized fast disintegrating/dissolving tablets (FDTs) that enhanced disintegration and dissolution of deferasirox, a drug with poor solubility and bioavailability. Although there are conventional oral tablets and tablets for oral…
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