Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
Scaling Tableting Processes from Compaction Simulator to Rotary Presses—Mind the Sub-Processes
Compaction simulators are frequently used in the formulation and process development of tablets, bringing about the advantages of flexibility, low material consumption, and high instrumentation to generate the most possible process understanding. However, their capability of resembling general…
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Image-based Characterization of Powder Flow to Predict the Success of Pharmaceutical Minitablet…
Powder flowability plays an important role in die filling during tablet manufacturing. The present study introduces a novel small-scale measuring technique for powder flow. Based on image analysis, the flow was defined depending on the variation of luminous intensity and the movement of powder…
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Overview of the Advantages and Disadvantages of Different Mucosal Sites for the Delivery of…
Nanoparticles (NPs) often improve the efficacy of therapeutic actives, and their delivery to mucosal sites allows for unique and localized effects compared to parenteral delivery. Sites of mucosal surfaces includes the eyes, nasal cavity, lungs, and the entire gastrointestinal tract from mouth to…
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Impact of Particle and Equipment Properties on Residence Time Distribution of Pharmaceutical…
Paddle feeders are devices commonly used in rotary tablet presses to facilitate constant and ecient die filling. Adversely, the shear stress applied by the rotating paddles is known to affect the bulk properties of the processed powder dependent on the residence time. This study focuses on the…
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A Mathematical Approach to Consider Solid Compressibility in the Compression of Pharmaceutical…
In-die compression analysis is an effective method for the characterization of powder compressibility. However, physically unreasonable apparent solid fractions above one or apparent in-die porosities below zero are often calculated for higher compression stresses.
One important reason for this…
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Control of oral absorption of nutritional supplement using lipid-based formulations (LBFs):…
Among various formulations for oral use, lipid-based formulation (LBF) has been expected as a promising technology to improve the absorption of poorly water-soluble compounds. In the current study, three types of LBFs were tested for their effects on the extent, rate and variability of oral…
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Liposomes for Enhanced Bioavailability of Water-Insoluble Drugs: In Vivo Evidence and Recent…
It has been known that a considerable number of drugs in clinical use or under development are water-insoluble drugs with poor bioavailability (BA). The liposomal delivery system has drawn attention as one of the noteworthy approaches to increase dissolution and subsequently absorption in the…
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Nanostructured Lipid Carriers: A Groundbreaking Approach for Transdermal Drug Delivery
Nanostructured lipid carriers (NLCs) are novel pharmaceutical formulations which are composed of physiological and biocompatible lipids, surfactants and co-surfactants. Over time, as a second generation lipid nanocarrier NLC has emerged as an alternative to first generation nanoparticles. This…
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Gastroretentive Microballons: A Novel Approach for Drug Delivery
Hollow microballoons (microspheres) are spherical empty particles without core. Microballoons (Hollow microsphere) are a drug delivery system that promises to be a potential approach for gastric retention. Microballoons drug-delivery systems are based on a noneffervescent system containing empty…
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Development of an Orodispersible Film Containing Stabilized Influenza Vaccine
Most influenza vaccines are administered via injection, which is considered as userunfriendly. Vaccination via oral cavity using an orodispersible film (ODF) might be a promising alternative. To maintain the antigenicity of the vaccine during preparation and subsequent storage of these ODFs, sugars…
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