Pharma Excipients
Orally Dissolving Technology Excipient
Enhanced Loading Efficiency and Mucoadhesion Properties of Gellan Gum Thin Films by Complexation…
Polymeric oral thin films (OTFs) were prepared by the casting method, combining gellan gum (GG), a water-soluble polysaccharide, and glycerol (Gly) as a plasticizing agent. GG-Gly films were investigated as potential systems for buccal drug delivery using fluconazole (Class I of the…
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Novel Water-Soluble Lubricant for the Preparation of Tiemonium Methylsulfate Fast-Dissolving Tablets
The rapid delivery and self-administration of antispasmodics are very essential for the treatment of pain associated with smooth muscle spasms. Tiemonium methylsulfate (TMS) is a well-known antispasmodic drug used in the treatment of muscle spasms of different organs. New oral dissolving tablets…
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Development and Evaluation of Astaxanthin Orally Disintegrating Tablets Prepared from Coprocessed…
The world’s population is aging; therefore, conventional pharmaceutical dosage forms designed for adult are not suitable. Orally disintegrating tablets (ODTs) are innovative dosage forms designed to overcome the problem of difficulty in swallowing or dysphagia, which is a common problem among all…
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New Generation direct compression excipient for ODTs
HiSORAD is a state-of-the-art co-processed excipient for orally disintegrating tablets designed to have well-balanced property between oral disintegration time and tablet hardness.
HiSORAD is composed of three compendial grade excipients, D-Mannitol, Microcrystalline cellulose and Croscarmellose…
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Orodispersible Tablets (ODTs) – Overcoming you main challenges
Orally Disintegrating Tablets (ODTs) are getting increasingly interesting delivery systems in the pharmaceutical and nutraceutical fields. They are an innovative way to handle the product lifecycle management, generate market differentiation, and increase the interest of consumers.
This webinar…
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Mucoadhesive bilayered buccal platform for antifungal drug delivery into the oral cavity
A drug delivery technology comprising a mucoadhesive bilayered buccally anchored tablet containing natamycin was developed. The concept was to anchor the tablet to the buccal tissue and allow controlled release of the drug through the matrix into the mouth. Carbomer (Carbopol ® 974 P NF) was used to…
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Sublingual tablets containing spray-dried carvedilol-loaded nanocapsules: development of an…
The aim of this study was to propose the use of spray-dried mucoadhesive carvedilol-loaded nanocapsules in the formulation of sublingual tablets. There is no previous report describing the preparation of tablets containing spray-dried nanocapsules or tablets containing nanocapsules, neither prepared…
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StarLac® for Orally Disintegrating Tablets
Oral application of drugs is not only the most common way for systemic drug application, it is also patient’s route of choice. Oral formulations are – compared to injections or infusions – convenient and painless. As they do not require sterility they are cost effective and reveal good patient…
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Development and Characterization of Liquisolid Tablets Based on Mesoporous Clays or Silicas for…
The aim of this work was to evaluate the effectiveness of mesoporous clays or silicas to develop fast-dissolving glyburide tablets based on a liquisolid approach. Selected clay (Neusilin®US2) and silica (Aeroperl®300) allowed preparation of innovative drug liquisolid systems containing…
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Electrospun Orodispersible Films of Isoniazid for Pediatric Tuberculosis Treatment
Child-appropriate dosage forms are critical in promoting adherence and effective pharmacotherapy in pediatric patients, especially those undergoing long-term treatment in low-resource settings. The present study aimed to develop orodispersible films (ODFs) for isoniazid administration to children…
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