Pharma Excipients
Orally Dissolving Technology Excipient
Desloratadine-Loaded Flexible Orally Dissolvable Tablets Made of Electrospun Fiber Mats
Patient compliance and personalized dose adjustments are important factors, especially in pediatric care. Orodispersible tablets (ODTs) are gaining importance as they increase patient compliance compared to other solid oral dosage forms. ODTs are solid dosage forms that disintegrate within seconds…
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The Development of Oral Solid Dosage Forms Using the Direct-Compression Tableting of Spray-Dried…
Abstract
This study addresses the challenge of developing a cheap, patient-friendly alternative to antibiotics using bacteriophages for gastrointestinal applications. It explores the feasibility of manufacturing an enteric solid dosage form containing a salmonella-specific Myoviridae phage, Felix…
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Roquette Introduced New Chapter in Moisture Protection at CPhI 2023
Press Release
La Madeleine (France), 25th October 2023 – Roquette, a global leader in plant-based ingredients and leading provider of pharmaceutical and nutraceutical excipients, is pleased to announce the addition of three new excipient grades to its unmatched portfolio of solutions for moisture…
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The Impact of Polymer Mixture Composition on the Properties of Electrospun Membranes for Drug…
Orally dispersible films (ODFs) prepared by an electrospinning are a novel type of pharmaceutical formulation. This dosage form has the potential to be beneficial for small children and the elderly, who can have problems with administration of classical tablets due to the increased risk of choking…
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Drug Dissolution in Oral Drug Absorption: Workshop Report
Abstract
The in-person workshop “Drug Dissolution in Oral Drug Absorption” was held on May 23–24, 2023, in Baltimore, MD, USA. The workshop was organized into lectures and breakout sessions. Three common topics that were re-visited by various lecturers were amorphous solid dispersions (ASDs),…
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Adult Patients with Difficulty Swallowing Oral Dosage Forms: A Systematic Review of the Quantitative…
Abstract
The aim of this systematic review was to identify and critically appraise the available evidence regarding solid oral dosage forms (SODFs), e.g., tablets, and challenges regarding the oral administration of medicine to inpatients in a variety of healthcare settings such as (1) hospitals,…
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Formulation and in vitro evaluation of pramipexole orally disintegrating tablets for pediatric…
Abstract
In this study, orally disintegrating tablets (ODT) of pramipexole dihydrochloride monohydrate (PPX) was developed with direct compression method by using ready-to-use excipients Parteck® ODT, Pharmaburst® 500, Ludiflash®, F Melt®, and Prosolv® Easytab SP for pediatric restless leg syndrome…
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Development of concentration prediction models for personalized tablet manufacturing using…
Abstract
In this work, concentration prediction models applicable to a very wide range of concentrations for personalized tablet manufacturing were developed using near-infrared (NIR) spectroscopy. Tablet manufacturing experiments were conducted, and NIR spectral data of the tablets were obtained.…
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Formulation and In Vitro Evaluation of Taste- Masked Prednisolone Orodispersible Tablets
Abstract
Background: Prednisolone is a corticosteroid with a very bitter taste acts as anti- anti-inflammatory and immune suppressant drug and it is used at any age.
Objective: To improve patient compliance by masking the bitter taste of the drug to be delivered as an orodispersible tablet.…
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The effect of polymeric binder type and concentration on flow and dissolution properties of SMEDDS…
Self-microemulsifying drug delivery systems (SMEDDS) are lipid-based formulations, designed to improve the solubility of poorly-water soluble drugs. Mesoporous silica is frequently used for SMEDDS solidification by various techniques. One of them is wet granulation, which enables achieving both high…
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