Pharma Excipients
Orally Dissolving Technology Excipient
3D Printed Tablets (Printlets) with Braille and Moon Patterns for Visually Impaired Patients
Visual impairment and blindness affects 285 million people worldwide, resulting in a high public health burden. This study reports, for the first time, the use of three-dimensional (3D) printing to create orally disintegrating printlets (ODPs) suited for patients with visual impairment. Printlets…
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Orally disintegrating drug carriers for paediatric pharmacotherapy
Non-compliance, dosing inaccuracy, choking risk, flavour, and instability, are some of the issues associated with paediatric, oral dosage forms — tablets, capsules, solutions, and suspensions. Orally disintegrating drug carriers, a dosage form with growing interest, are thought to overcome several…
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Formulation and Characterisation of Carbamazepine Orodispersible 3D-Printed Mini-Tablets for…
Abstract
One of the main challenges to paediatric drug administration is swallowing difficulties, hindering the acceptability of the medicine and hence clinical outcomes. This study aims at developing a child-appropriate dosage form, the orodispersible mini-tablet (ODMT), using the model drug…
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Advances in Formulation and Manufacturing Strategies for the Delivery of Therapeutic Proteins and…
Therapeutic proteins and peptides (TPPs) are increasingly favoured above small drug molecules due to their high specificity to the site of action and reduced adverse effects resulting in increased use of these agents for medical treatments and therapies. Consequently, there is a need to formulate…
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Downstream Processing of Amorphous Solid Dispersions into Orodispersible Tablets
The formulation development of amorphous solid dispersions (ASDs) towards a patient-friendly oral solid dosage form is proving to be still challenging. To increase patient’s compliance orodispersible tablets (ODTs) can be seen as promising alternative. Two different ASDs were prepared via hot melt…
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Drugs for neglected tropical diseases: availability of age-appropriate oral formulations for young…
It is recognised that paediatric indications and age-appropriate formulations are required to ensure that paediatric populations receive appropriate pharmacotherapeutic treatment. The lack of information on dosing, efficacy and safety data (labelling) is a well-recognised problem for all diseases…
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Overview on Functionality Added Co-processed Excipients for Orodispersible Tablets
Orally disintegrating tablets are an emerging trend in novel drug delivery system and have received ever increasing demand during the last few decades. Orally disintegrating tablets ODTs are the dosage form which will disintegrate in mouth within seconds without need of water. This type of property…
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Preparation and Evaluation of Directly Compressible Orally Disintegrating Tablets of Cannabidiol…
This study demonstrated the implementation of a liquisolid technique to formulate directly compressible orally disintegrating tablets (ODTs). Cannabidiol (CBD), a hydrophobic cannabinoid, was prepared as a liquisolid powder using microcrystalline cellulose–colloidal silicon dioxide as a…
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Formulate Robust, Fast Disintegrating Tablets with polyplasdone® crospovidone – Webinar
Do you want to learn how to optimize immediate release formulations in terms of disintegration performance?
Then register for our next free webinar:
Formulate Robust, Fast Disintegrating Tablets with polyplasdone® crospovidone.
Due to the complex interrelationships between raw material…
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High-Shear Wet Granulation of SMEDDS Based on Mesoporous Carriers for Improved Carvedilol Solubility
Mesoporous carriers are a convenient choice for the solidification of self-microemulsifying drug delivery systems (SMEDDS) designed to improve the solubility of poorly water-soluble drugs. They are known for high liquid load capacity and the ability to maintain characteristics of dry, free-flowing…
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