Pharma Excipients
Orally Dissolving Technology Excipient
Formulation development and evaluation of taste masked anthelmintics chewable tablets by using…
The aim of the current study is to develop and evaluate patient friendly taste masked anthelmintics chewable tablets for pediatrics and geriatrics use. However, the chewable tablets have to disintegrate in the mouth before swallowing, which makes the chewable tablet dosage forms inappropriate for…
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A Promising Single Oral Disintegrating Tablet for Co-Delivery of Pitavastatin Calcium and Lornoxicam…
Significance: Statins are an important class of drugs that help to control hyperlipidemia, and one of these statins recently used is pitavastatin calcium (PITA). Nevertheless, the most reported adverse effect of statins is myopathy. Therefore, combining statins with non-steroidal anti-inflammatory…
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Orodispersible films: Conception to quality by design
Orodispersible films (ODFs) are pharmaceutical dosage forms that do not need water to be ingested. Perfect for paediatrics and geriatrics
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Utilization of Ethylcellulose Microparticles with Rupatadine Fumarate in Designing Orodispersible…
Minitablets in orodispersible form constitute a flexible drug delivery tool for paediatric and geriatric population as they eliminate the risk of chocking and do not require drinking water in the application. Due to their direct contact with taste buds, taste sensation is an important factor.…
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Newly designed punch for scored tablets: Evaluation by an expert system based on quality by design
Scored tablets enable modulation of the drug dose and intake by elderly, pediatric and dysphagic patients. However, they are known to involve difficulties in splitting, problems of mass uniformity of portions and loss of mass on breaking. A new punch designed for manufacturing of convex-faced…
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Optimized Taste-Masked Microparticles for Orally Disintegrating Tablets as a Promising Dosage Form…
The objective of this research was to optimize the tasted-masked microparticles for orally disintegrating tablets containing donepezil hydrochloride using quality risk assessment and design of experiment approaches. The double emulsion solvent evaporation technique using aminoalkyl methacrylate…
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Fabrication and Characterization of Fast-Dissolving Films Containing Escitalopram/Quetiapine for the…
Major depressive disorder (MMD) is a leading cause of disability worldwide. Approximately one-third of patients with MDD fail to achieve response or remission leading to treatment-resistant depression (TRD). One of the psychopharmacological strategies to overcome TRD is using a combination of an…
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Developing and evaluation of orodispersible tablets containing caffeine
Starting from the premise that a reduced number of active pharmaceutical ingredients (APIs) are used to treat hypotension, the aim of this study consisted of developing new formulations of caffeine-orodispersible tablets (CAF- ODTs). The formulation variables were the type of disintegrant…
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Poster: Granfiller-D® & Hisorad® As New Co-processed Excipients For Orally Disintegrating…
Introduction: Tablets are still the most widely used dosage form for oral application due to their simple administration and relatively low manufacturing costs. One main disadvantage of tablets is the difficulty in swallowing or chewing. This is especially relevant for special patient groups, e.g.…
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Application of mini ODTs and coin-shaped ODTs with high performance excipients for pediatric…
There is strong clinical need for pediatric formulations from healthcare professionals and caregivers since the number of available pediatric formulation is limited. Currently oral administration is the main route of administration for pediatric formulations in the market. For development of…
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