Pharma Excipients
Calcium CarbonateCMC and Croscarmellose Sodium
Effect of Binder Attributes on Granule Growth and Densification
The rate and extent of granule growth and densification during high-shear wet granulation (HSWG) depends on a variety of formulation and process variables, including material attributes of critical formulation excipients, such as binders. The effects of known binder attributes to the rate and extent…
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Orally disintegrating dosage forms
What is an orally disintegrating dosage form?
An orally disintegrating tablet is a novel formulation that dissolves in the saliva within a few seconds and without requiring of drinking additional water. This dosage form is a powerful way to deliver active drugs ingredients because it has many…
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A novel approach to support formulation design on twin screw wet granulation technology:…
The overall objective of this work is to understand how excipient characteristics influence the drug product quality attributes and process performance of a continuous twin screw wet granulation process. The knowledge gained in this study is intended to be used for Quality by Design (QbD)-based…
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AN INVESTIGATION INTO TASTE MASKING OF A MICRONIZEDPARACETAMOL USING AQUACOAT® ECD APPLIED VIA…
INTRODUCTION AND PURPOSE
Taste masking is a very important step in the development of paediatric medications such as oral suspensions and tablets for products with APIs that are bitter or unpalatable. In this study, taste masking of a bitter, micronized API model (Paracetamol) was…
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