HPMC – Hydroxypropylmethylcellulose

SYNOPSIS Controlled release (CR) formulations are revolutionizing drug delivery across the pharmaceutical landscape. Offering advantages like enhanced therapeutic outcomes and patient convenience, this innovative drug formulation is experiencing rapid global growth. The popularity of CR…
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Abstract The use of a process analytical technology has been demonstrated using near-infrared spectroscopy for continuous manufacturing of pharmaceutical formulations and is within the scope of the U.S. Food and Drug Administration's real-time release testing initiative. While effective for simple…
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IFF officially release a new Controlled release platform on 15th of May 2024. Here you get a deeper insight in the  "Timing is Everything" platform where you can learn about pharmaceutical formulations to benefit patients and the importance of controlled release of active ingredients. No…
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Abstract In the nasal cavity, nasal mucosa had a high blood perfusion rate, due to this the absorption of the drug is high as compared to other routes, as well as has increased good bioavailability of drugs at the systemic circulation. To improve the nasal retention time of in-situ gel with nasal…
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Orodispersible films (ODFs) have emerged as innovative pharmaceutical dosage forms, offering patient-specific treatment through adjustable dosing and the combination of diverse active ingredients. This expanding field generates vast datasets, requiring advanced analytical techniques for deeper…
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PRESS RELEASE NEW YORK —May 15, 2024 — IFF (NYSE:  IFF), a global leader in food and beverage, home and personal care and health, today announced a new controlled release platform for its portfolio of controlled release products including METHOCEL™, ETHOCEL™, and POLYOX™.  Under the banner,…
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Conventional spray drying using a 2-fluid nozzle forms matrix microparticles, where drug is distributed throughout the particle and may not effectively mask taste. In contrast, spray drying using a 3-fluid nozzle has been reported to encapsulate material. The objective of this study was to spray dry…
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Hydroxy propyl methyl cellulose (Hypromellose) and methyl cellulose are produced by Shin-Etsu Chemical Co., Ltd. since 1960s under the trade name METOLOSE®. For methyl cellulose, several grades are available, and they differ in viscosity.For hydroxy propyl methyl cellulose they differ in viscosity…
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Shin-Etsu Chemical supplies the various excipients for pharmaceutical industry and developed PHARMACOAT® in the 1960s during the early days of film coating and since then it has been the subject of a continuous development and quality improvement. The PHARMACOAT® grades are low viscous…
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This study aimed to develop a novel pH-modified nanoparticle with improved solubility and oral bioavailability of poorly water-soluble celecoxib by modifying the microenvironmental pH. After assessing the impact of hydrophilic polymers, surfactants and alkaline pH modifiers on the drug solubility,…
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