Browsing Category
HPMC – Hydroxypropylmethylcellulose
Exploring Immersion Coating as a Cost-Effective Method for Small-Scale Production of Enteric-Coated…
Abstract
The coating process for solid dosage forms is widely used in the pharmaceutical industry but presents challenges for small-scale production, needed in personalized medicine and clinical or galenic settings. This study aimed to evaluate immersion coating, a cost-effective small-scale…
Read More...
Read More...
3D Printing Direct Powder Extrusion in the Production of Drug Delivery Systems: State of the Art and…
Abstract
The production of tailored, on-demand drug delivery systems has gained attention in pharmaceutical development over the last few years, thanks to the application of 3D printing technology in the pharmaceutical field. Recently, direct powder extrusion (DPE) has emerged among the…
Read More...
Read More...
The most recent advances in liquisolid technology: Perspectives in the pharmaceutical industry
Abstract
Hydrophobic drugs exhibit altered bioavailability and pose other challenges at an industrial level due to their poor solubility and dissolution rates. In addition, poor flowability, compressibility, complex dosing schedules, and light-sensitivity problems associated with hydrophobic…
Read More...
Read More...
Continuous Manufacturing of Highly Drug Loaded Matrix Pellets by ProCell® Technology
This poster by Glatt Pharmaceutical Services was presented at the PBP World Meeting 2024:
Introduction
ProCell® Technology is a continuous spouted bed pelletization process which allows the manufacture of pellets with very high active drug loadings (> 95 %) and narrow particle size…
Read More...
Read More...
Liquisolids: A Modernistic approach in Drug Delivery System
Abstract
Liquisolid Technology aims to make drug entities more soluble that have low solubility and low permeability, through the cosolvency theory in a reasonably simple setup that doesn't require expensive technology. A non-volatile solvent is used to dissolve a medicine into molecular…
Read More...
Read More...
Spray-Dried Chitosan Hydrogel Particles as a Potential Delivery System for Benzydamine Hydrochloride
Abstract
Chitosan, being a biocompatible and mucoadhesive polysaccharide, is one of the most preferred hydrogel-forming materials for drug delivery. The objectives of the present study are to obtain spray-dried microparticles based on low-molecular-weight chitosan and study their potential…
Read More...
Read More...
Polymeric Nanohydrogel in Topical Drug Delivery System
Nanohydrogels (NH) are biodegradable polymers that have been extensively studied and utilized for various biomedical applications. Drugs in a topical medication are absorbed via the skin and carried to the intended location, where they are metabolized and eliminated from the body. With a focus on…
Read More...
Read More...
Colon-targeted 3D-Printed mesalamine tablets: Core-shell design and in vitro/ex-vivo evaluation
Abstract
Objectives
The present study is intended to develop a shell-core tablet using a hot melt extrusion (HME)-based dual-nozzle fused deposition modeling (FDM) three-dimensional (3D) printing approach. The primary objective was to establish a sustained-release colonic drug delivery system…
Read More...
Read More...
A Multi-Particulate Formulation of Pantoprazole Based on Enteric Coated Minitablets
JRS Pharma presented three posters at the 2024 PBP World Meeting in Vienna. This is the first poster:
Introduction
Multiparticulate systems provide solutions to some of the main challenges found with gastro-resistant formulations, namely dose dumping, unpredictable gastric retention time, and lack…
Read More...
Read More...
Fabrication of 3D-Printed Hydrocortisone Triple Pulsatile Tablet Using Fused Deposition Modelling…
Hydrocortisone (HC) is the optimal drug for adolescents diagnosed with congenital adrenal hyperplasia (CAH). Because traditional dosage regimens HC are inconvenient, our study used fused deposition modeling (FDM) three-dimensional (3D) printing technology to solve the problems caused by traditional…
Read More...
Read More...