Pharma Excipients
Organic Chemicals
Actual Sugars
Artificial Sweeteners
Carbohydrates
Cellulose
Cellulose Esters
Cellulose Ethers
CMC and Croscarmellose Sodium
Converted Starch
Dried Starch
Ethyl Cellulose
HPC - hydroxypropyl cellulose
HPMC - Hydroxypropylmethylcellulose
Microcrystalline Cellulose
Modified Starch
Starch
Sugar Alcohols
Sugars
Trehalose
IFF and BASF collaborate on the Virtual Pharma Assistant Platform ZoomLab™
PRESS RELEASE
NEW YORK — Nov. 8, 2023 — IFF and BASF today announced a collaboration between the Pharma Solutions divisions of both companies, to onboard IFF’s leading product brands in pharmaceutical excipients into BASF’s Virtual Pharma Assistant platform – ZoomLab™. The platform is a…
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Topical Delivery of Terbinafine HCL Using Nanogels: A New Approach to Superficial Fungal Infection…
This study investigated pH-responsive Terbinafine HCL (TBH)-loaded nanogels as a new approach to treating superficial fungal infections. Acrylic acid (AA) is a synthetic monomer that was crosslinked with a natural polymer (gelatin) using a free radical polymerization technique to fabricate…
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Design of experiments approach on the compaction properties of co-amorphous tablets
Co-amorphous systems are an evolving strategy to stabilize the amorphous form of a drug molecule with the aim of overcoming its poor water-solubility. With research focussing on the molecular level of co-amorphous systems, little is known about their downstream processing. In this study, tablets of…
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Segregation of Formulated Powders in Direct Compression Process and Evaluations by Small Bench-Scale…
Powder segregation can cause severe issues in processes of pharmaceutical drugs for control of content uniformity if the powder is likely to be free or easy flowing. Assessing segregation intensity of formulated powders in a process is challenging at the formulation stage because of the limited…
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Poly(ɛ-caprolactone) and Eudragit E blends modulate the drug release profiles from FDM printlets
Abstract
Thermoplastic polymers have been used to produce filaments by hot melt extrusion (HME), which can be applied to obtain 3D printlets by fused deposition modelling (FDM). Poly(ε-caprolactone) (PCL) is a low melting point thermoplastic polymer that provides HME filaments with excellent…
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Evaluation of the effect of granule size of raw tableting materials on critical quality attributes…
Abstract
Objective
The effects of granule size of raw materials on tablet hardness (TH) and weight (TW) in the continuous tablet manufacturing process (CTMP) were investigated using near-infrared spectroscopy (NIRS).
Methods
Granule materials of different sizes were prepared by extrusion…
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Detachable-Dissolvable-Microneedle as a potent subunit vaccine delivery device that requires no…
Although vaccine administration by microneedles has been demonstrated, delivery reliability issues have prevented their implementation. Through an ex vivo porcine skin experiment, we show visual evidence indicating that detachable dissolvable microneedles (DDMN) can deposit cargo into the dermis…
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Stability study of spray freeze-dried insulin dry powder formulations used for nose-to-brain…
Insulin is classified as a cold chain product due to being a peptide hormone with stability issues in the liquid preparation. Therefore, insulin was developed into the dry powder form to improve the stability and application for nose-to-brain delivery in Alzheimer’s disease treatment. Insulin was…
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A dry powder formulation for peripheral lung delivery and absorption of an anti-SARS-CoV-2 ACE2…
One of the strategies proposed for the neutralization of SARS-CoV-2 has been to synthetize small proteins able to act as a decoy towards the virus spike protein, preventing it from entering the host cells. In this work, the incorporation of one of these proteins, LCB1, within a spray-dried…
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Nitrite Content In Hydroxypropyl Methylcellulose
Introduction
N-nitrosamines are considered probable or possible carcinogens according to the International Agency for Research on Cancer, an agency within the World Health Organization (1).
Regulatory bodies across the world haverequested pharmaceutical companies to evaluate, investigate and…
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