Pharma Excipients
Organic Chemicals
Actual Sugars
Artificial Sweeteners
Carbohydrates
Cellulose
Cellulose Esters
Cellulose Ethers
CMC and Croscarmellose Sodium
Converted Starch
Dried Starch
Ethyl Cellulose
HPC - hydroxypropyl cellulose
HPMC - Hydroxypropylmethylcellulose
Microcrystalline Cellulose
Modified Starch
Starch
Sugar Alcohols
Sugars
Trehalose
The Preparation and Evaluation of Cyanocobalamin Mucoadhesive Sublingual Tablets
Cobalamin (vitamin B12), an essential vitamin with low oral bioavailability, plays a vital role in cellular functions. This research aimed to enhance the absorption of vitamin B12 using sublingual mucoadhesive tablets by increasing the residence time of the drug at the administration site. This…
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Formulation and In Vitro Evaluation of Taste- Masked Prednisolone Orodispersible Tablets
Abstract
Background: Prednisolone is a corticosteroid with a very bitter taste acts as anti- anti-inflammatory and immune suppressant drug and it is used at any age.
Objective: To improve patient compliance by masking the bitter taste of the drug to be delivered as an orodispersible tablet.…
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Polyenylphosphatidylcholines as bioactive excipient in tablets for the treatment of liver fibrosis
Liver fibrosis is a condition characterized by the accumulation of extracellular matrix (ECM) arising from the myofibroblastic transdifferentiation of hepatic stellate cells (HSCs) occurring as the natural response to liver damage. To date, no pharmacological treatments have been specifically…
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Biocompatible hydroxy double salt tablet formulations
Generally, commercial extended release tablets are core-based, which can cause problems for certain patients if they split them prior to ingestion. There is a need to develop non-core-based extended release tablets. We have previously reported the synthesis of two new biocompatible hydroxy double…
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Study of Microcrystalline Cellulose as a Substitute of Magnesium Stearate Towards Functionality of…
Abstract
In pharmaceutical industries, magnesium stearate is used as a lubricating agent. It is frequently used in the solid dosage forms. In solid dosage forms generally it is used in the concentration of 0.2 % to 2.0%. However, it decreases hardness of tablet in some formulations.…
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Investigation of Dispersion Kinetics of Particulate Lubricants and their Effect on the Mechanical…
Abstract
Introduction
Tablets are commonly produced by internally adding particulate lubricants, which are known to possibly lower the mechanical strength of tablets. This reduction is caused by the coverage of matrix forming components by lubricant particles, resulting in decreased…
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Optimization of radial extrusion and pellet coating processes using pat approaches
FDA's initiative Pharmaceutical CGMPs for the 21st century opened the door for introduction of several risk based approaches in pharmaceutical industry. One significant advancement that has emerged is the implementation of process analytical technology (PAT), which has opened doors for understanding…
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Nagase/Hayashibara will be attending the AAPS 2023 PharmSci 360 in Orlando
Press release
Nagase/Hayashibara will be attending the AAPS 2023 PharmSci 360 in Orlando, FL, USA.
AAPS 2023 PharmSci 360 in Orlando, FL, Orange County Convention Center
Nagase/Hayashibara Booth #3046
Poster Session M0930-04-23, Oct 23, 9:30-10:30
Title: Beneficial Effects of Trehalose…
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Structural modifications for the conversion of proteins and peptides into stable dried powder…
The drying of biomolecules into powdered formulations has become the main form of long-term product stabilisation, allowing for the delivery of safe and efficient medicines. Stability of proteins and peptides during the drying process is paramount for product quality. Drying macromolecules with an…
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Flow behavior under shear cell analysis of two HMPC grades
Abstract
A comparative analysis was conducted to examine the flow characteristics of two HPMC grades and their fractions. Excipients processing contains critical steps in the manufacturing of solid dosage forms and therefore it is essential to determine their flowability. Flow characterization was…
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