Pharma Excipients
Organic Chemicals
Actual Sugars
Artificial Sweeteners
Carbohydrates
Cellulose
Cellulose Esters
Cellulose Ethers
CMC and Croscarmellose Sodium
Converted Starch
Dried Starch
Ethyl Cellulose
HPC - hydroxypropyl cellulose
HPMC - Hydroxypropylmethylcellulose
Microcrystalline Cellulose
Modified Starch
Starch
Sugar Alcohols
Sugars
Trehalose
Immediate-release dosage form; focus on disintegrants use as a promising excipient
Disintegrants are materials or mixtures of substances added in the drug formulations, which make easier dispersion or breakup of tablets and ingredients of capsules in small-scale particles for fast dissolution then it comes in contact with water in the GI tract. Immediate drug release dosage forms…
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Silicified Microcrystalline Cellulose, Modern Co-Processed Excipient For Low Dose Solid Dosage Forms
ABSTRACT
Low dose 75 mg aspirin tablets are widely used for adults in arthritis, rheumatic fever, pain and to reduce uric acid
excretion. Low dose formulation are manufactured by wet granulation method, which is time consuming and
laborious. However these days direct compression method is in…
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Effect of Moisture Content of Excipient (Microcrystalline Cellulose)
Abstract
Quality of pharmaceutical product is very important because pharmaceuticals drugs should be safe and therapeutically active formulation performance should be consistent and predictable. Final product quality depends on all ingredients which is used for making the final product tablet.…
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Development and Optimization of a Novel Lozenge Containing a Metronidazole-Peppermint Oil-Tranexamic…
In-depth studies on essential oil–based nanoemulsions (NEs) have centered on a variety of oral health issues. NEs improve the delivery of nonpolar active agents to sites and thereby boost the dissolution and distribution of the agents. Metronidazole-peppermint oil-tranexamic acid…
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Investigating the Impact of Co-processed Excipients on the Formulation of Bromhexine Hydrochloride…
Abstract
Purpose
Orodispersible tablets (orally disintegrating tablets, ODTs) have been used in pharmacotherapy for over 20 years since they overcome the problems with swallowing solid dosage forms. The successful formula manufactured by direct compression shall ensure acceptable mechanical…
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Leveraging a multivariate approach towards enhanced development of direct compression extended…
Extended release formulations play a crucial role in the pharmaceutical industry by maintaining steady plasma levels, reducing side effects, and improving therapeutic efficiency and compliance. One commonly used method to develop extended release formulations is direct compression, which offers…
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Uncovering advances in final end-user applications, user acceptability, quality assurance, and…
The increasing demand for innovative drugs and personalized treatment is radically changing the pharmaceutical industry, where significant efforts in research and development (R&D) are taking place. Three-dimensional (3D) printing offers interesting solutions for these demands, solving some of…
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Effect of Different Types of Wood Pulp on Hydrolysis Reaction Time and Degree of Polymerization of…
Abstract
Different types of wood pulps are used to manufacture microcrystalline cellulose. Percentage of alpha cellulose depends on type of wood pulp. Both wood pulp soft and hard wood pulp are usually used to manufacturing microcrystalline cellulose. Though the production process of wood pulp has…
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Fenofibrate loaded nanofibers based thermo-responsive gel for ocular delivery: Formulation…
This research work is to develop nanofiber loaded in -situ gel for the delivery of fenofibrate to the posterior ocular site. Fenofibrate had showed its efficacy in neovascular ocular diseases under clinical studies but its low aqueous solubility makes difficult to develop a suitable ocular…
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Amorphous nasal powder advanced performance: in vitro/ex vivo studies and correlation with in vivo…
Abstract
Purpose
Amorphous solid dispersions (ASD) for nasal delivery offer the opportunity to increase drug release performance, while using polymers with mucoadhesive properties. The aim of the present study was to apply this solubility enhancement technique to a poorly soluble drug for nasal…
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