Pharma Excipients
Organic Chemicals
Actual Sugars
Artificial Sweeteners
Carbohydrates
Cellulose
Cellulose Esters
Cellulose Ethers
CMC and Croscarmellose Sodium
Converted Starch
Dried Starch
Ethyl Cellulose
HPC - hydroxypropyl cellulose
HPMC - Hydroxypropylmethylcellulose
Microcrystalline Cellulose
Modified Starch
Starch
Sugar Alcohols
Sugars
Trehalose
Modeling the Impact of Excipients Selection on Nitrosamine Formation towards Risk Mitigation
Abstract
Risk control for nitrosamine impurities in drug products is currently a major challenge in the industry. Nitrosamines can form during drug product manufacturing and storage through the reaction of nitrites with amine-containing APIs or impurities. The level of nitrites in excipients and…
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A Machine Learning Approach to Qualitatively Evaluate Different Granulation Phases by Acoustic…
Wet granulation is a frequent process in the pharmaceutical industry. As a starting point for numerous dosage forms, the quality of the granulation not only affects subsequent production steps but also impacts the quality of the final product. It is thus crucial and economical to monitor this…
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Synergistic stabilization of emulsion gel by nanoparticles and surfactant enables 3D printing of…
Pharmaceutical formulation of oral dosage forms is continuously challenged by the low solubility of new drug candidates. Pickering emulsions, emulsions stabilized with solid particles, are a promising alternative to surfactants for developing long-term stable emulsions that can be tailored for…
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The impact of common pharmaceutical excipients on the gut microbiota
ABSTRACT
Introduction
Increasing attention is being afforded to understanding the bidirectional relationships that exist between oral medications and the gut microbiota, in an attempt to optimize pharmacokinetic performance and mitigate unwanted side effects. While a wealth of research has…
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New Asahi Kasei Website to Provide Solutions for Your Oral Solid Dose Formulation Needs
Asahi Kasei announces the launch of their new website. The new website should provide a more intuitive and user-friendly experience to the existing and prospective customers.
Over last 50+ years, Asahi Kasei has been leading manufacturer and supplier of the microcrystalline products for the…
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Comparison between polymeric excipients using SeDeM expert system in combination with mathematical…
Based on the quality by design approach, we used the SeDeM expert system to assess seven polymers of different chemical nature and molecular weight for their use in direct compression. Because the SeDeM system fails by not evaluating the mechanical properties of materials, we used the Heckel and…
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AVICEL® PH LN – A Low Nitrite Microcrystalline Cellulose
Pharma Solutions at IFF provides you access to one of the broadest microcrystalline cellulose (MCC) portfolios in the industry. Backed by decades of innovation, and expertise, Avicel® PH offers a long history of manufacturing the highest-quality pharmaceutical grade MCC.
Our deep polymer…
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Integrated in vitro – In vivo – In silico studies in the pharmaceutical development of propranolol…
In order to exploit the advantage of drug delivery through the buccal mucosa, mucoadhesive buccal films with propranolol hydrochloride based on polyethylene oxide, hydroxypropyl methylcellulose, and polyvinyl alcohol have been developed. The aim of this study was the development,…
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Optimization and Evaluation of Lisinopril Mucoadhesive Sustained Release Matrix Pellets: In-Vitro…
Lisinopril (LIS) it is antihypertensive drug, classified as a class III drug with a high water solubility and low permeability. To overcome the low permeability, 32 factorial designs aimed to formulate LIS as a sustained-release (LIS-SR) matrix pellet by extrusion/spheronization. Matrix pellets were…
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Technical evaluation of precisely manufacturing customized microneedle array patches via inkjet drug…
Dissolvable microneedle array patches offer the possibility to deliver active pharmaceutical ingredients bypassing the gastrointestinal tract by piercing the stratum corneum. Usually, microneedles are produced by micromolding but this often results in a waste of active pharmaceutical ingredient. In…
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