Pharma Excipients
Organic Chemicals
Actual Sugars
Artificial Sweeteners
Carbohydrates
Cellulose
Cellulose Esters
Cellulose Ethers
CMC and Croscarmellose Sodium
Converted Starch
Dried Starch
Ethyl Cellulose
HPC - hydroxypropyl cellulose
HPMC - Hydroxypropylmethylcellulose
Microcrystalline Cellulose
Modified Starch
Starch
Sugar Alcohols
Sugars
Trehalose
3D screen printing technology enables fabrication of oral drug dosage forms with freely tailorable…
3D printing offers new opportunities to customize oral dosage forms of pharmaceuticals for different patient populations, improving patient safety, care, and compliance. Although several notable 3D print technologies have been developed, such as inkjet printing, powder-based printing, selective…
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Solid implantable devices for sustained drug delivery
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug administration routes. Oral and injectable drug administration are the most common routes for drug delivery providing peaks of drug concentrations in blood after administration followed by concentration decay…
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Comprehensive powder flow characterization with reduced testing
Powder flow is a critical attribute of pharmaceutical blends to ensure tablet weight uniformity and production of tablets with consistent and reproducible properties. This study aims at characterizing different powder blends with a number of different rheologic techniques, in order to understand how…
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Polyvinyl alcohol: Revival of a long lost polymer
Introduction
With target-oriented drug discovery and an increasing focus on specialized medicines, the manufacturing of final drug products is becoming more and more complex. The processing and formulation of active pharmaceutical ingredients (APIs) designed with a specific target and functionality…
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Moisture Behavior of Pharmaceutical Powder during the Tableting Process
Abstract
The moisture content of pharmaceutical powder is a key parameter contributing to tablet sticking during the tableting process. This study investigates powder moisture behavior during the compaction phase of the tableting process. Finite element analysis software COMSOL Multiphysics® 5.6…
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Pharmaceutical evaluation of Levofloxacin orally disintegrating tablet formulation using low…
We evaluated the pharmaceutical properties of levofloxacin (LV) in the form of an orally disintegrating tablet (LVODT) to find a new usefulness of low frequency (LF) Raman spectroscopy. LVODT contained dispersed granules with diameters in the order of several hundred micrometers, which were composed…
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Microneedles for Enhanced Topical Treatment of Skin Disorders: Applications, Challenges, and…
Microneedles (MNs) can be used for the topical treatment of skin disorders as they directly deliver therapeutics to the site of skin lesions, resulting in increased therapeutic efficacy while having minimum side effects. MNs are used to deliver different kinds of therapeutics (e.g., small molecules,…
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Ultra-High-Resolution Optical Coherence Tomography for the investigation of thin multilayered…
Optical Coherence Tomography (OCT) has recently gained attention as a promising technology for in-line monitoring of pharmaceutical film-coating processes for (single-layered) tablet coatings and end-point detection with commercial systems. An increasing interest in the investigation of…
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Characterization and Validation of a New 3D Printing Ink for Reducing Therapeutic Gap in Pediatrics…
Abstract
3D printing technology can be used to develop individualized medicines in hospitals and pharmacies, allowing a high degree of personalization and the possibility to adjust the dose of the API based on the quantity of material extruded. The main goal of incorporating this technology is to…
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On the Influence of Raw Material Attributes on Process Behaviour and Product Quality in a Continuous…
Continuous manufacturing of oral solids is a complex process in which critical material attributes (CMAs), formulation and critical process parameters (CPPs) play a fundamental role. However, assessing their effect on the intermediate and final product’s critical quality attributes (CQAs) remains…
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