Pharma Excipients
Starch
Comparison of Compressibility, Compactability, and Lubricant Sensitivity of Two Partially…
Modified starches are widely employed excipients in tablets compression. The ability of materials to deform under pressure (compressibility) and create strong compacts (compactability) is then important for tablet manufacture. This study aims to evaluate and compare two partially pregelatinized…
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Starch Products as Candidate Excipients in a Continuous Direct Compression Line
Direct compression (DC) remains the most preferred technique to produce tablets, and its effectiveness is directly influenced by raw material attributes. Therefore, the selection of specific grades of excipients to achieve desirable powder flow and compression properties is of importance. Shifting…
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Pharmatrans SANAQ® SL 004 co-processed Starch/Lactose excipient
Pharmatrans Sanaq now offers SANAQ® SL 004 as a co-processed excipient based on mix 15/85 of maize starch and lactose monohydrate.
SL 004 forms an ultra-uniform and highly compressible lactose excipient for tablet fillings that supports direct compression (DC) applications, aiding tablet…
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Integrated Twin-Screw Wet Granulation, Continuous Vibrational Fluid Drying and Milling: A fully…
Highly homogeneous low-dose (50 µg) tablets were produced incorporating perfectly free-flowing granules prepared by a fully integrated Continuous Manufacturing (CM) line. The adopted CM equipment consisted of a Twin-Screw Wet Granulator (TSWG), a Continuous Fluid Bed Dryer (CFBD) and a Continuous…
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Comparison of Compressibility, Compactability and Lubricant Sensitivity of Two Partially…
Modified starches are widely employed excipients in tablets compression. The ability of materials to deform under pressure (compressibility) and create strong compacts (compactability) is then important for tablet manufacture. This study aims to evaluate and compare two partially pregelatinized…
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LYCAGEL™ – Roquette’s Innovative Plant-Based Solution Unlocks Possibilities for Veggie Softgel…
Market-first plant-based softgel system provides a strong alternative to gelatin for nutraceutical and pharmaceutical manufacturers and marketers of softgel products
GENEVA, Illinois. (November 18, 2020) - Roquette, a global leader in plant-based ingredients, pioneer of plant proteins and…
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Insights into the Moisture Scavenging Properties of Different Types of Starch in Tablets Containing…
Starch is a commonly used excipient in the pharmaceutical industry. However, information on the effect of the moisture scavenging properties of starch to protect moisture-sensitive drugs is limited. The interaction between starch and moisture is of particular interest as moisture fugacity can impact…
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Effect of Disintegrants on Prolongation of Tablet Disintegration Induced by Immersion in Xanthan…
In clinical practice, a thickening solution is frequently used to allow easy swallowing of tablets by patients suffering from dysphagia. This study investigated the effect of the thickening solution on tablet disintegration. Model tablets containing different disintegrants were prepared and their…
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Starch-based controlled release matrix tablets: Impact of the type of starch
Different types of starches were used to prepare controlled release tablets loaded with diprophylline by direct compression. The impact of the natural origin of the starch, potential chemical modifications (e.g., cross-linking with phosphate or adipate, hydroxypropylation, acetylation to different…
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Development and Characterization of Pullulan-based Orally Disintegrating Films Containing Amlodipine…
The aim of this study was to prepare pullulan-based orally disintegrating films (ODFs) containing amlodipine besylate, an anti-hypertensive drug, by the solvent casting method. For this purpose, nine different ODF formulations (F1-F9) were prepared by using different plasticizers (glycerol,…
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