Pharma Excipients
Starch
Development of a Starch-Based Co-processed Excipient for Direct Compression applying DoE
23. October 2017 The development of novel excipients with enhanced functionality has been explored using particle engineering by co-processing. The aim of this study was to improve the functionality of tapioca starch (TS) for…
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StarCap 1500® Co-Processed Starch Excipient
17. September 2017
StarCap 1500 is a unique co-processed mixture of globally accepted excipients, corn starch and pregelatinized starch, designed for use in capsules and tablets.
StarCap 1500 is an inert free-flowing compressible excipient with excellent disintegration…
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Wheat in pharmaceutical Excipients – which excipients are based on it – is it a gluten…
18. August 2017
How many wheat (derived) excipients contain wheat / wheat starch as apotential source of Gluten? Based on available information most of the excipients such as Sodium StarchGlycolate, Pregelatinized starch and native starches are based on corn and potato…
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Pregelatinized hydroxypropyl pea starch as matrix forming material for lyophilized orodispersible…
07. August 2017
Abstract
Oral fast-disintegrating dosage forms, also known as ‘fast-disintegrating’ or ‘fast-dissolving’ dosage forms, are a relativelynovel dosage technology that involves the rapid disintegration or dissolution of the dosage form. The objective of…
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Evaluation of retrograded starch as excipient for controlled release matrix tablets
15. June 2017
Abstract
High amylose starch (HAS) was retrograded by two different methods. The physicochemical properties of the retrograded materials were evaluated and structural changes were highlighted. Micromeritics properties were demonstrated as suitable for…
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An explorative analysis of process and formulation variables affecting comilling in a vibrational…
31. May 2017
Abstract
Praziquantel, a BCS II class anthelmintic drug used for the treatment of schistosome infections, was coground in a vibrational mill with different polymers (linear and crosslinked povidone, copovidone and sodium starch glycolate). An explorative…
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Physical modification and characterization of starch using pregelatinization and co- process of…
24. March 2017
Abstract. Starch is an economical excipient that is used in oral dosage form. It has poor compressibility and flowability. Pregelatinization and co-process as a physical modification technique have been conducted widely; nevertheless, the single…
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Superdisintegrants:introduction to chemistry and Performance – DFE Pharma
16. February 2017
Superdisintegrants: Introduction to chemistry and Performance - DFE Pharma
Summary
The superdisintegrants Primojel® (sodium starch glycolate) and Primellose® (croscarmellose sodium) are cross-linked and substituted polymers of glucose. The degree of…
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Functional Assessment of Four Types of Disintegrants and their Effect on the Spironolactone Release…
16. February 2017
Abstract
Spironolactone is a drug derived from sterols that exhibits an incomplete oral absorption due to its low water solubility and slow dissolution rate. In this study, formulations of spironolactone with four disintegrants named as…
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Pharmaceutical applications of native starch in conventional drug delivery : Starch
14. February 2017
Abstract
Starch is a naturally occurring polymer that is present in many green plants. Its nontoxic and nonirritant properties, as well as low cost, ease of modification, and versatility in use have placed starch in a leading position among polymers…
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