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Trehalose
Effect of Process Parameters, Protectants and Carrier Materials on the Survival of Yeast Cells…
The administration of living microorganisms is of special interest, with regard to probiotic microorganisms providing health benefits to the patient. Effective dosage forms require the preservation of microbial viability until administration. Storage stability can be improved by drying, and the…
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Alternative Excipients for Protein Stabilization in Protein Therapeutics: Overcoming the Limitations…
Given their safety and efficiency in protecting protein integrity, polysorbates (PSs) have been the most widely used excipients for the stabilization of protein therapeutics for years. In recent decades, however, there have been numerous reports about visible or sub-visible particles in…
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Trehalose in Biomedical Cryopreservation–Properties, Mechanisms, Delivery Methods, Applications,…
Cells and tissues are the foundation of translational medicine. At present, one of the main technological obstacles is their preservation for long-term usage while maintaining adequate viability and function. Optimized storage techniques must be developed to make them safer to use in the clinic.…
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Impact of Formulation design and Lyophilization on the Physicochemical Characteristics of…
Aim
The fundamental purpose of this study was to develop a stable lyophilized finasteride nanosystem (FNS-NS) for topical delivery.
Methods
The FNS-NS was fabricated using an ultrasonication technique. The impact of two different cryoprotectants on the physicochemical characteristics of…
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Progress on Thin Film Freezing Technology for Dry Powder Inhalation Formulations
The surface drying process is an important technology in the pharmaceutical, biomedical, and food industries. The final stage of formulation development (i.e., the drying process) faces several challenges, and overall mastering depends on the end step. The advent of new emerging technologies paved…
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Trehalose SG – For Exosome Production and Storage brochure
Mesenchymal Stem Cell (MSC)-derived Exosomes
Trehalose SG MSC-derived exosomes are attracting attention for their application in regenerative medicine, drug delivery, diagnostics and cosmetics, and the need for a stable supply of exosomes is increasing.
The addition of TREHALOSE…
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Novel trehalose-based excipients for stabilizing nebulized anti-SARS-CoV-2 antibody
COVID-19 is caused by the infection of the lungs by SARS-CoV-2. Monoclonal antibodies, such as sotrovimab, showed great efficiency in neutralizing the virus before its internalization by lung epithelial cells. However, parenteral routes are still the preferred route of administration, even for local…
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Trehalose SG – Exosomes brochure
Hayashibara ― A world leading supplier of pharmaceutical grade Trehalose SG
Founded as a starch syrup manufacturer in 1883, Hayashibara has grown into a company with strong research and development expertise, engaging in original and creative research. Utilizing our technological background in…
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Trehalose SG – For DNA/RNA Stabilization brochure
Hayashibara ― A world leading supplier of pharmaceutical grade Trehalose SG
Founded as a starch syrup manufacturer in 1883, Hayashibara has grown into a company with strong research and development expertise, engaging in original and creative research. Utilizing our technological background in…
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Construction of Bio-conjugated nano-vesicles using non-ionic surfactants for targeted drug delivery:…
Introduction
Targeted delivery of drugs to the brain is a complicated activity. This complication is caused by the blood–brain barrier (BBB). Interestingly, there are various transporters on the surface of the BBB that are naturally used for the transportation of specific compounds. A practical…
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