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Paediatric
Orphan Formulations for Pediatric Use: Development and Stability Control of Two Sildenafil Citrate…
Sildenafil citrate causes vasodilatation, relaxation of the smooth muscle, and reduction of pulmonary arterial pressure. The latter property makes sildenafil citrate efficient for the treatment of cardiovascular diseases, including pulmonary arterial hypertension. Pediatric patients with pulmonary…
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Effects of Formulation Excipients on Skin Barrier Function in Creams Used in Pediatric Care
Semisolid dosage forms are recommended for the dermal care of babies and children.
If we look at the ingredients of these preparations, there are still many cases in which there are
substances (occlusive agents, preservatives) that no longer meet certain requirements of the modern
age, so it is…
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Comparison of Different Liquid and Semisolid Vehicles Selected for Oral Administration of Pellets…
The acceptability and palatability of a dosage form are extremely important to improve patient compliance. Mixing oral solid dosage forms with food carriers is often necessary to ease swallowing and provide the taste-masking effect. The present research investigated how a liquid or semisolid carrier…
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3D printed gummies: Personalized drug dosage in a safe and appealing way
Obtention of customized dosage forms is one of the main attractions of 3D printing in pharmaceuticals. In this sense, children are one of the groups within the population with a greater need for drug doses adapted to their requirements (age, weight, pathological state…), but most 3D printed oral…
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Development of a stable oral pediatric solution of hydrochlorothiazide by the combined use of…
Hydrochlorothiazide (HCT) is widely used in pediatrics for hypertension management. Due to the lack of pediatric commercial forms, community or hospital pharmacies generally prepare HCT extemporaneous pediatric suspensions by dispersing in water a portion of a crushed tablet or the drug powder;…
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European Paediatric Formulation Initiative – 12th EuPFI Conference
It is our great pleasure to welcome you to the EuPFI 12th Annual Conference. The Scientific Committee, together with the EuPFI members, have been working diligently to prepare for the first virtual EuPFI conference. While we are disappointed that we will not be together in-person with you this year,…
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Pediatric dosage forms—challenges and recent developments: A critical review
Pediatric population is a diverse group comprising of different subgroups. The use of unlicensed and off-label medicines for treating children is widespread due to the non-availability of suitable dosage forms for this age group. Although the physiological differences related to the diverse age…
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Online Seminar Multiparticulates
Multiparticulates such as micropellets, pellets, granules and mini-tablets represent modern and innovative technology platforms. Multiparticulates can provide a number of advantages compared with larger-sized monolithic forms such as tablets. Increasing compliance is achieved for children – from…
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High-Dose Methotrexate-Induced Idiopathic Intracranial Hypertension in Infant Acute Lymphoblastic…
A 7-month-old female patient with B-cell acute lymphoblastic leukemia (ALL) developed recurring anterior fontanelle bulging after completing both of her first and second courses of high-dose methotrexate (HD-MTX) induction. She did not, however, show any other abnormal neurological examinations,…
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ADAPT Aspirin Dose Accuracy in PaediaTrics – a survey
ADAPT is a research project which enables researchers from the University of Birmingham to work with nurses and pharmacists involved in the manipulation of tablets to provide doses for children.
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