What is the World Tuberculosis Day? Each year, WHO commemorates World Tuberculosis (TB) Day on March 24 to raise public awareness about the devastating health, social and economic consequences of TB, and to step up efforts to end the…

The present Special Issue on Drug Delivery and Translational Research in Europe brings together representative examples of the work being carried out in pharmaceutical laboratories, both within universities or research institutions, and in…

Transdermal delivery has the advantage of bypassing the first-pass effect and allowing sustained release of the drug. However, the drug delivery is limited owing to the barrier created by the stratum corneum. Microneedles are a transdermal…

The current situation, heavily influenced by the ongoing pandemic, puts vaccines back into the spotlight. However, the conventional and traditional vaccines present disadvantages, particularly related to immunogenicity, stability, and…

Glaucoma is considered to be one of the biggest health problems in the world. It is the main cause of preventable blindness due to its asymptomatic nature in the early stages on the one hand and patients’ non-adherence on the other. There…

Considering microneedles (MNs) as transdermal drug delivery tools is driven by some crucial factors among which easy handling, simple administration and better patient compliance are primary. Achievable tailored microneedle production…

Although dissolving microneedles have garnered considerable attention as transdermal delivery tools, insufficient drug loading remains a challenge owing to their small dimension. Herein, we report a one-step process of synthesizing…

Highlights Novel hydrogel-forming microneedles were produced. Their physicochemical properties were promising. Methotrexate was successfully delivered in vitro and in vivo. Methotrexate (MTX) is one of the mainstays of…

Microneedle arrays (MNA) are considered as one of the most promising resources to achieve systemic effects by transdermal delivery of drugs. They are designed as a minimally invasive, painless system which can bypass the stratum corneum,…