A week ago I wrote about the importance of new and novel excipients for the pharmaceutical industry and presented Klucel™ xtend and BioSustane™ in last week´s edition of "The Excipients Week". In the meantime I launched a small poll with…

The pharmaceutical industry needs innovative, new and novel excipients solutions to support the developments in next generation therapeutics, new manufacturing concepts (eg. continuous manufacturing, 3Dprinting, etc.), drug delivery and API…

Addition of pharmaceutical excipients is a commonly used approach to decrease the viscosity of highly concentrated protein formulations, which otherwise could not be subcutaneously injected or processed. The variety of protein–protein…

Thermogelling amphiphilic block copolymers have been widely investigated in the development of pharmaceutical drug carriers. In particular, thermosensitive gels based on poloxamer 407 (P407) have great potential for periodontal disease…

Background: Various potential effect of drugs on alleviating diseases by regulating intestinal microbiome as well as the pharmaceutical excipients on gut microbiota has been revealed. However, the interaction between them is rarely…

Direct compression (DC) is the simplest and most economical way to produce pharmaceutical tablets. Ideally, it consists of only two steps: dry blending of a drug substance(s) with excipients followed by compressing the powder mixture into…

This article gives criteria for choosing excipients in liquisolid technology. Liquisolid technology is applicable for non polar drugs by converting drug solution into dry free flowing powder. Patient compliance is more in oral route of…

See an overview of the IOI Oleo specialties for Veterinary Applications. They are used for companion as well as for farm animals in following uses: • Injectables - SC and IM • Infusions - IV • Oral (e.g. paste, drench) • Pour-on…

This study is based on near-infrared spectroscopic detection technology to achieve 100% classification of in-class and out-of-class pharmaceutical ingredients and excipients by support vector machine model.4 types of 8 different…

Moisture sorption by polymeric carriers used for the development of amorphous solid dispersions (ASDs) plays a critical role in the physical stability of dispersed drugs since moisture may decrease glass transition temperature (Tg) and…