10. June 2015 The application of bad tasting, often bitter APIs to children requires in most cases an effective taste optimisation. This can be achieved either by the…
Abstract
A promising solution to customize oral drug formulations for the pediatric population has been found in the use of 3D printing, in particular Fused Deposition Modeling (FDM) and Semi-Solid Extrusion (SSE). Although formulation…
Abstract
Compounded medicines are widely used, especially for pediatric patients. The aim of this study was to evaluate children’s acceptability of compounded preparations and to provide information regarding compounding practices'…
Enteral feeding tubes (EFTs) can be placed in children diagnosed with HIV which need nutritional support due to malnutrition. EFTs are the main route for medication administration in these patients, bringing up concerns about off label use…
Abstract
Carvedilol (CARV) -a nonselective β-receptor antagonist indicated in treatment of hypertension- suffers from poor oral bioavailability due to its poor solubility and hepatic first-pass metabolism. This study aimed to optimize…
Abstract
Ivermectin has been used since the 1980s as an anthelmintic and antiectoparasite agent worldwide. Currently, the only available oral formulation is tablets designed for adult patients. A patient-friendly orodispersible tablet…
Abstract
Pediatric pharmacotherapy presents distinctive challenges compared with adult pharmacotherapy and encompasses considerations such as drug administration methods, susceptibility to medication-related toxicity, and taste…
Abstract
The bitter drug, warfarin, has a narrow therapeutic index (NTI) and is used in paediatrics and geriatrics. The aim of this feasibility study was to formulate the taste-masked warfarin-containing pellets to be applicable for dose…
Abstract
Three-dimensional printing (3DP) technology in pharmaceutical areas is leading to a significant change in controlled drug delivery and pharmaceutical product development. Pharmaceutical industries and academics are becoming…
This poster by Glatt Pharmaceutical Services was presented at the PBP World Meeting 2024:
Introduction
ProCell® Technology is a continuous spouted bed pelletization process which allows the manufacture of pellets with very high…