Tablets are the most common pharmaceutical dosage form - but why, and what are they? In this video PharmaDrama aka Prof. Simon Gaisford discusses what tablets are, what they contain, how they are made and how you should take them. He also…

Ibuprofen loaded and unloaded alginate aerogel particles were successfully coated with methacrylic acid-ethyl acrylate copolymer in a Wurster fluidized bed. Pores of both aerogels were well-preserved during the coating process. Effects of…

It has been seventy years since a water-soluble version of vitamin E called tocophersolan (also known as TPGS) was produced; it was approved by USFDA in 1998 as an inactive ingredient. Drug formulation developers were initially intrigued by…

The powder flowability of active pharmaceutical ingredients and excipients is a key parameter in the manufacturing of solid dosage forms used to inform the choice of tabletting methods. Direct compression is the favoured tabletting method;…

Although previous research demonstrated improved flowability, packing, fluidization, etc. of individual powders via nanoparticle dry coating, none considered its impact on very low drug loaded blends. Here, fine ibuprofen at 1, 3, and 5 wt%…

In recent years, 3D printing has attracted great interest in the pharmaceutical field as a promising tool for the on-demand manufacturing of patient-centered pharmaceutical forms. Among the existing 3D printing techniques, direct powder…

Three-dimensional (3D) printing is drastically redefining medicine production, offering digital precision and personalized design opportunities. One emerging 3D printing technology is selective laser sintering (SLS), which is garnering…

Since late 2019, concerns regarding trace levels of the probable human carcinogen N-dimethylnitrosamine (NDMA) in Metformin-containing pharmaceuticals have been an issue if they exceeded the maximum allowable intake of 96 ng/day for a…

Expert System for Drug Development, i.e. SeDeM Expert System (Span. Sistema Experto para DEsarrollo de Medicamentos) represents a method intended for evaluation of powder properties affecting processability, particularly compression…

Pellet production is a multi-step manufacturing process comprising granulation, extrusion and spheronisation. The first step represents a critical control point, since the quality of the granule mass highly influences subsequent process…