The design and scale-up of spray dried particle delivery systems
28. April 2017 Areas covered: The review firstly presents a systematic analysis of the trends in development of particle delivery systems using spray drying. This is…
Drug Product Development for Older Adults—Multiparticulate Formulations
26. October 2016 Abstract The multiparticulate drug product concept covering micropellets, pellets, and mini-tablets is presented as a highly feasible approach to present…
Process analytical technology in Downstream-Processing of Drug Substances – A review
Abstract
Process Analytical Technology (PAT) has revolutionized pharmaceutical manufacturing by providing real-time monitoring and control capabilities throughout the production process. This review paper comprehensively examines the…
Learn and enhance your skills in formulation and tableting thanks to STYL’One Nano
In the rapidly evolving field of pharmaceutical sciences, innovative tools and technologies are essential to advancing research and development. One such innovative instrument is the STYL'One Nano, offered by MEDELPHARM. This compact yet…
From lab to industrial development of lipid nanocarriers using quality by design approach
Abstract
Lipid nanocarriers have attracted a great deal of interest in the delivery of therapeutic molecules. Despite their many advantages, compliance with quality standards and reproducibility requirements still constrain their…
3D printed electro-responsive system with programmable drug release
Abstract
Precision medicine is the next frontier in pharmaceutical research, aiming to improve the safety and efficacy of therapeutics for patients. The ideal drug delivery system (DDS) should be programmable to provide real-time…
Unveiling the Mystery of Soft Gelatin Capsules
Soft Gelatin Capsules (SGCs), commonly known as softgels, have transformed drug delivery since their invention. Despite their 19th-century origins, their widespread adoption only began in the 20th century, thanks to technological…
Real-time release testing of in vitro dissolution and blend uniformity in a continuous powder…
Abstract
Continuous manufacturing is gaining increasing interest in the pharmaceutical industry, also requiring real-time and non-destructive quality monitoring. Multiple studies have already addressed the possibility of surrogate in…
The influence of milling of ribbons on selected granule quality attributes and carvedilol release…
Abstract
Roller compaction is gaining importance in the pharmaceutical industry. This study evaluates the impact of ribbon milling conditions on properties of granules and compression mixtures and on drug release from hypromellose-based…
A review of hot melt extrusion technology: Advantages, applications, key factors and future…
Abstract
After decades of development, hot melt extrusion (HME) technology has matured as a well-established pharmaceutical methodology. Through the process of extruding both drug and carrier materials in a molten state under specific…