The objectives of this study were to evaluate the delamination of convex-shaped metformin HCl (MF) and evogliptin tartrate (EG) multi-layer tablets depending on the pre-compression and main compression pressures and simultaneously correlate…

Photodynamic therapy (PDT) recently has been shown as a promising option in the treatment of premalignant lesions of the soft oral tissues. Effective delivery of photosensitizer is challenging due to poor drug adherence to the oromucosal…

Press Release Clariant Health Care expands the range of functional excipients to solve active pharmaceutical ingredient (API) delivery & bioavailability challenges New effective carrier systems for drug delivery in different…

Benjamin Gavinet did an interesting presentation at the APGI Skin and Formulation conference in Nantes at the beginning of October. We did a small interview with him summarizing the most important topics and results of his presentation.…

Processed excipients (PEs) function in creating various dosage forms and need no introduction. For instance, recent studies have shown that PEs oleic acid, which is used with the breast cancer medicine Herceptin, functions both as a liquid…

Abstract Objective: The present study is aimed to design, development of nanoemulgel and evaluate for topical drug delivery system. Nanoemulgel prove to be promising carrier for intense amount of poorly penetrable drugs to produce their…

Abstract Amorphous solid dispersions (ASDs) enable formulations to improve the solubility of poorly soluble active pharmaceutical ingredients (APIs). The amorphous state is reached through the disruption of the crystalline lattice of an…

Introduction N-nitrosamines are considered probable or possible carcinogens according to the International Agency for Research on Cancer, an agency within the World Health Organization (1). Regulatory bodies across the world…

In a 2003 survey conducted by the American Association of Pediatrics, unpleasant taste was identified as the most significant barrier to completing treatment in pediatrics. Drug taste masking is extremely relevant to improve patient…

Oral colon delivery has widely been pursued exploiting naturally occurring polysaccharides degraded by the resident microbiota. However, their hydrophilicity may hinder the targeting performance. The aim of the present study was to…