In case of colon-specific delivery of therapeutic agents through oral route, microbial/enzyme-triggered release approach has several advantages over other approaches due to unique microbial ecosystem in the colon. Multiple-unit carriers…

Targeting celecoxib to the ileo-colonic region could be beneficial for the treatment and prevention of colon cancer. Ileo-colonic targeting can be achieved by using pH-dependent coating systems such as ColoPulse. Celecoxib has poor aqueous…

Inulin is a heterogeneous green polysaccharide obtained from natural sources. It is found in a variety of regularly eaten vegetables, fruits, cereals, and in their roots and rhizomes including onion, leek, wheat, garlic, dahlia, asparagus,…

Geared towards our clients' operational requirements, the idea behind this investment is to speed up the launch of new products to meet the emerging needs of our key markets. The 2500m² Toulouse Technology Center hosts 50 experts and…

A single-tablet-scale mixing process, being part of a setup for the production of individualized tablets, is developed and studied. The process relies on the principle of vibratory mixing to achieve a homogeneous powder blend in the order…

The drying unit of a continuous from-powder-to-tablet manufacturing line based on twin-screw granulation (TSG) is a crucial intermediate process step to achieve the desired tablet quality. Understanding the size reduction of pharmaceutical…

Alginates are biopolymers that have been investigated for their use in food and medical fields. Minimal information is available regarding their potential application as tablet superdisintegrants. Here we studied the disintegration action…

In this study, powder flowability is assessed during granular compaction under free surface conditions by using Hausner ratio (HR) as flowability index. Different kinds of pharmaceutical and food powders were examined. The assessment of the…

Developing new pharmaceuticals is costly and time-consuming. New methods are always in demand for various stages of product development. Investing in the early phases of development can save a significant amount of resources in the long…

Tablets constitute about 80–90% of dosage forms commonly prescribed by medical practitioners for therapeutic management of disease conditions. It is a solid dosage form that exercises advantages over other dosage forms because of its ease…