The majority of drugs (around 60%) are formulated as a salt. This says salts are important! But why? And what are they exactly? Here, PharmaDrama aka Prof. Simon Gaisford discusses the basic definition of a salt, how they are formed and why…

Abstract The 3–dimensional printing process (3DP) was patented in the 1980s, but the utilization of this process has expanded substantially over the past decade, to which the pharmaceutical industry is a major contributor. With increasing…

Oral mucositis in the oral cavity, caused by radiation therapy and chemotherapy, requires personalized care and therapy due to variations in the lesions of patients. In the present study, we fabricated a model of personalized oral film…

Additive manufacturing allows for designing innovative properties to pharmaceutical products. Binder jetting (BJ) 3D printing is one of the key techniques within innovative manufacturing. In this study, a structured approach according to…

The low water solubility of pharmacoactive molecules limits their pharmacological potential, but the solubility parameter cannot compromise, and so different approaches are employed to enhance their bioavailability. Pharmaceutically active…

Amorphous solid dispersion (ASD) is a preparation widely used for improving the solubility and low oral absorbability of poorly water-soluble drugs, but the quantitative analysis of its dissolution profiles and its supersaturation status…

The eye is an organ with limited drug access due to its anatomical and physiological barriers, and the usual forms of ocular administration are limited in terms of drug penetration, residence time, and bioavailability, as well as low…

Drug overdose connected to marketed pharmaceutical products, particularly opioids, occurs at an alarming rate. Novel strategies through innovative formulation approaches that reduce the likelihood of overdose while allowing safe therapeutic…

Background The purpose of this research was to compare the effect of shape factors of biconvex compacts on prediction of dilution potential from polynomial regression models of area ratio-mass fraction data of novel α-lactose…

Pharmaceutical tablet productions by direct compaction (DC) are more environmentally sustainable than wet granulation (WG) owed to DC’s lower energy consumption. For drug particles with poor flowability, however, the environmental benefits…