Drug delivery technology has a wide spectrum, which is continuously being upgraded at a stupendous speed. Different fabricated nanoparticles and drugs possessing low solubility and poor pharmacokinetic profiles are the two major substances…

Aqueous Solubility of Bio actives plays a significant role in Drug, Biopharma, Food, Dietary and Cosmetic formulations. Poor solubility is one of the biggest hurdles in developing these formulations as well as desired therapeutic effect. It…

Find a summary of the most popular posts on excipients and formulation of the last week: Top posts of the week #1 Combating Coronavirus: Key Role of Cyclodextrins in Treatment and Prevention #2 Curcumin-loaded solid self-emulsifying drug…

Many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution rates in aqueous environments such as the luminal fluids of the gastrointestinal tract. The oral bioavailability of these compounds is usually very…

Internal aqueous phase was incorporated in solid lipid nanoparticles (SLNs) containing 5 lipid components to form dual-phase SLNs (DPSLNs), which were then conjugated with transferrin (Tf) to transport nerve growth factor (NGF), rosmarinic…

Abstract: Chitosan is an excipient which has been studied thoroughly in research works thanks to its positive characteristics such as muco-adhesiveness and ability to open epithelial-tight-junctions. In this article, lipophilic stearoyl…

The lipolysis test is recommended during lipid-based formulation (LBF) development to evaluate whether the prototype formulations should be able to solubilize and maintain the drug in solution during the ‘in vivo’ digestion process. It is…

Gelucire® is Gattefossé’s brand of semi-solid excipients originally designed for hard gelatin capsule molding. The name results from the fusion between « gélule » meaning capsule and « cire » meaning wax. Following the name, there is a set…

02. June 2018 The aim of the study is the evaluation of the impact of glyceryl ester surfactants on cell permeating properties of SEDDS (self-emulsifying drug delivery…