Ability to predict the porosity, and its reduction after nano-silica dry coating, based on the Bond number and cohesion force estimated via multi-asperity contact model was examined for twenty different pharmaceutical powders. A new model…

Here is BIOGRUNDs step-by-step guide how to prepare a suspension. Please be aware that all parameters have to be adjust individually. Equipment & Material Equipment: propeller stirrer, beaker Material: Water, AquaPolish Here…

Scaling up fluidised bed coating of microparticles with particle size smaller than 150 µm is a challenge because of the high tendency of particle agglomeration. Consequently, the production yield of coating trials are unsatisfactory and low…

Pharma Excipients and BASF Pharma are presenting a live webcast together on the newly launched enteric-release coatings module of ZoomLab™. Monday, 28 September 2020 – 03:00 PM CEST Drug product development is currently based on…

Tablet film coating is a common but critical process providing various functionalities to tablets, thereby meeting diverse clinical needs and increasing the value of oral solid dosage forms. Tablet film coating is a technology-driven…

Various active pharmaceutical ingredients (APIs) are either aggressive to the stomach’s mucosa or vulnerable to the acidic nature of the gastric juice. Solid oral dosage forms carrying one of these APIs thence require gastric resistant…

Coating of particles is a widely used technique in order to obtain the desired surface modification of the final product, e.g., specific color or taste. Especially in the pharmaceutical industry, rotor granulators are used to produce round,…

In the tablet film coating process, especially when it comes to large tablets especially with the size more than ø9mm, friability can be an issue at the early stage of the process. The purpose of the experiment was to confirm if Ceolus™…

Various active pharmaceutical ingredients (APIs) are either aggressive to the stomach’s mucosa or vulnerable to the acidic nature of the gastric juice. Solid oral dosage forms carrying one of these APIs thence require gastric resistant…

Although Raman spectroscopy has been described as a potential process analytical technique for tablet coating, it has rarely been transferred from academic studies to commercial manufacturing applications. The reasons for this are probably…