Oxytocin is a nonapeptide hormone used in labor to initiate uterine contractions and to prevent and treat postpartum hemorrhage. Oxytocin is currently administered by injection and requires refrigerated transport and storage, which limits…

The objective of this research was to optimize the tasted-masked microparticles for orally disintegrating tablets containing donepezil hydrochloride using quality risk assessment and design of experiment approaches. The double emulsion…

Protein delivery systems have been extensively applied in controlled releasing of protein or polypeptides for therapeutic treatment or tissue regeneration. While 3D printing technology shows great promise in novel dosage form with tailoring…

The objective was to develop a reservoir-type nimesulide gel patch for controlled drug delivery and avoid the gastrointestinal adverse effects associated with the oral delivery of nimesulide. Six patch formulations of nimesulide gel…

Introduction: Pharmaceutical, chemical, cosmetic, food, and other industries utilize various processes to modify particle properties, where agglomeration of particles occurs either as an accurately controlled process or as an undesired…

Measles (Me) and rubella (Ru) viral diseases are targeted for elimination by ensuring a high level of vaccination coverage worldwide. Less costly, more convenient MeRu vaccine delivery systems should improve global vaccine coverage,…

Comprehensive understanding of an integrated continuous pharmaceutical technology was achieved in this study by a combining design of experiments and mechanistic modeling-based simulations. The powder to granule line consisted of twin-screw…

Nanostructured lipid carriers (NLCs) are a nano-particulate carrier system consisting of solid lipids, liquid lipids, emulsifying agents, and water. NLCs have gained continuous significance in recent times and have displayed tremendous drug…

The present work aimed to formulate intranasal insulin fast-dissolving films for treatment of anosmia in patients post COVID-19 infection. Variant films were prepared employing the casting method and using hydroxypropyl methyl cellulose and…