See the sixth issue of Fuji Chemical Industries Technical Newsletter: Directly compressible excipient system for fast-Disintegrating oral tablets*, F-MELT® formulations are designed with a focus on three important characteristics of…

The current paper shows how excipient properties impact the process parameters and the final tablet properties in a fully integrated continuous direct compression line. Blend properties of low-dose (1% w/w) and high-dose (40% w/w) …

Aqueous film coating is a common and important step in the production of most pharmaceutical tablets. Controlling this process is beneficial to maintain stable and optimal operation and the use of a model capable of describing its main…

TaBlitz™ – Redefining and connecting the tablet design process from formulation to manufacturing The TaBlitz platform is tailored to streamline the pharmaceutical industry's product development and manufacturing processes. This is achieved…

Glioblastoma (GB) is one of the most lethal types of neoplasms. Its biologically aggressive nature and the presence of the blood-brain barrier (BBB) limit the efficacy of standard therapies. Several strategies are currently being developed…

The current study aimed to develop a topical emulgel of dasatinib (DTB) for rheumatoid arthritis (RA) treatment to reduce systemic side effects. The quality by design (QbD) approach was employed to optimize DTB-loaded nano-emulgel using a…

This paper presents surrogate models of dissolution behavior to identify the critical input parameters in tablet manufacturing processes. Dissolution behavior is a critical quality attribute, and is defined as the time profile of fraction…

A QbD-DM3 strategy was used to design ketoprofen (KTF) optimized liquid (L-SNEDDS) and solid self-nanoemulsifying drug delivery systems (S-SNEDDS). Principal component analysis was used to identify the optimized L-SNEDDS containing Capmul®…

Quality for your formulation, stability for your products. To solve the challenge of stability requirements in plasma applications, we offer a wide range of high-quality pharmaceutical excipients that allow you to formulate and…

Reduce risk and overcome challenges Ophthalmic drugs pose special formulation challenges to manufacturers. In general, choosing the right processes and materials is important to ensure the required quality, drug tolerability and patient…