Betulinic acid (BA) is a bioactive molecule with antineoplastic, antiviral, anti-inflammatory features; however, it exhibits low solubility in water, which limits its practical applications. Our work aims to develop self-nanoemulsifying…

Biodegradable polymeric nanocapsules (NC) present incredible characteristics as drug nanocarriers that optimize drug targeting. However, However, a more detailed isolated effect of polymer-based nanoparticles as drug carriers is required.…

Cancer refers to a collection of diseases that have abnormal cell growth as their hallmark. This inability of cytotoxic agents to distinguish between rapidly dividing healthy cells andrapidly multiplying cancerous cells produces the most…

Inflammatory diseases present with dysregulated inflammatory reactions and oxidative stress, resulting in heavy health-associated economic burden to society. Current mainstream therapies, including traditional therapies such as steroids,…

Hesperetin (HT) is a polyphenolic compound with anti-carcinogenic, tumor necrosis, and anti-oxidant properties. The present study reports the fabrication, optimization, and evaluation of HT-loaded nanosponges (HTN)- based gel (HTNG) for…

The present study describes the formulation, optimization and characterization of quercetin loaded nanosuspension. The formulation was prepared using liquid antisolvent precipitation technique. Optimization of formulation was done using Box…

Curcumin (CU) possesses diverse pharmacological activities while being relatively safe; nevertheless, its clinical application is limited due to its physico-chemical characteristics. This study aimed to synthesize cinnamic acid based…

In this work, three different functionalized mesoporous silica nanoparticles (MSNs) were synthesized through the co-condensation synthesis in oil/water emulsion. Hexadecyltrimethoxysilane, triethoxy-3-(2-imidazolin-1-yl)propylsilane and…

Labrafil M2125-CS is a non-ionic surfactant component widely used for improving the solubilization of poor water-soluble drugs and as component of lipid-based nanosystem formulation. The aim of this research work was to evaluate in depth…

The COVID-19 crisis has alerted the research community to re-purpose scientific tools that can effectively manage emergency pandemic situations. Researchers were never so desperate to discover a 'magic bullet' that has significant clinical…