Inorganic polyphosphate (polyP) is a morphogenetically active and metabolic energy-delivering physiological polymer that is released from blood platelets. Here, we show that polyP efficiently inhibits the binding of the envelope spike…

An international study involving the Institute of Nanotechnology of the Cnr has found that quercetin acts as a specific inhibitor for the virus responsible for Covid-19, showing a destabilizing effect on 3CLpro, one of the key proteins for…

The antiviral agent remdesivir (Veklury®; Gilead Sciences), nucleotide analogue prodrug, has broad-spectrum activity against viruses from several families. Having demonstrated potent antiviral activity against coronaviruses in preclinical…

Another week full of great scientific publications - find the one you liked most! Top post of the last 30 days is still "How to improve API Bioavailability?"as you can also see in the Top post of 2020. Top posts of the week #1…

The host immune system is highly compromised in case of viral infections and relapses are very common. The capacity of the virus to destroy the host cell by liberating its own DNA or RNA and replicating inside the host cell poses challenges…

Another week full of great scientific publications - find the one you liked most! Top posts of the week #1 Hot-Melt Extrusion – Enabling Technologies from Dupont #2 Tablet Quality-Prediction Model - Toward Flexible Switching Between…

Remdesivir, an investigational broad-spectrum antiviral agent, has shown in vitro activity against SARS-CoV-2. To maximize direct delivery to the target site, the lungs, we aim to develop remdesivir as a dry powder for inhalation using thin…

The trending interest on how to improve API bioavailability goes on. The second week in a row the most viewed post on pharma excipients is now also ranking as the top post of the year. Let's see what is coming next! Top posts of the week…

You have you missed the most popluar articles of this week? No worries you will find them here. It seems that the reaction on the question "How to improve API Bioavailability" is a major concern in the industry and reflects the evolution in…