The drying capacity of a continuous vibrated fluid bed dryer was studied using a DoE by varying microcrystalline cellulose content in the formulation, water amount in the twin-screw granulation, inlet air temperature, air flow rate and the…

Abstract Nutraceutical herbal medicine and supplements demand increases day by day. Herbal medicine normally contains lipids, protein, carbohydrate, vitamins, minerals and other necessary nutrients depending upon their emphases. Generally,…

In this work, the performance of two fast chemical imaging techniques, Raman and near-infrared (NIR) imaging is compared by utilizing these methods to predict the rate of drug release from sustained-release tablets. Sustained release is…

ABSTRACT The solid dosage form is the easiest method of administering drugs for systemic effect. All dosages forms are made by two main components one is API and second is excipient. Excipient is present in bulk quantity and is required…

Extended-release tablets, also known as sustained-release, controlled-release, or time-release tablets, have become increasingly important in the healthcare sector due to their ability to maintain consistent drug levels in the body over a…

Abstract The pharmaceutical industry has traditionally manufactured medicines in a limited range of dose strengths, with an emphasis on addressing the needs of the largest patient subgroups. This has disadvantaged smaller patient subsets,…

Summary Continuous production has now been adopted even in the pharmaceutical industry and is indispensable in current product developments. This study focuses on the process of continuous direct compression, with the aim of guaranteeing…

Hypromellose, a widely used polymer in the pharmaceutical industry, is available in several grades, depending on the percentage of substitution of the methoxyl and hydroxypropyl groups and molecular weight, and in various functional forms…

This paper presents a machine learning-based image analysis method to monitor the particle size distribution of fluidized granules. The key components of the direct imaging system are a rigid fiber-optic endoscope, a light source and a…

During the development of pharmaceutical spray-dried formulations, many samples must be prepared for physico-chemical characterisation and dissolution testing by systematically varying parameters such as drug loading or the grades and…