Nanoencapsulation is a promising approach to enhance the therapeutic potential of a drug. Herein, three selected naphthoquinone (NTQ) derivatives, based on the IC50 value against Trypanosoma evansi, were encapsulated using gum damar as…

INTEGRATED CDMO SERVICES FOR LIPID-NANOPARTICLE-BASED GENETIC DRUGS AND OTHER NANOMEDICINES SINCE THE 1990S Evonik Vancouver Laboratories, formerly known as Transferra Nanosciences Inc. or Northern Lipids, has been a market CDMO leader for…

Purpose Hyaluronic acid (HA) nanogel has hyaluronic acid in the main chain, a hydrophilic, biocompatible material with low toxicity, and a hydrophobic group in the side chain. A nanoordered gel is spontaneously formed, due to its…

Enhancing cannabinoids’ therapeutic efficacy In our previous technical note, we reported on the encapsulation of CBD vs THC (1) into lipid-based nanoparticles. The work here-in continues on that theme in terms of studying the differences…

The world of nutraceutical tablet formulation is complex and many critical values have to be considered during development - like dissolution properties, shelf-life stability, or exposure to environmental challenges (oxygen, light, humidity…

Silica nanoparticles have entered clinical trials for a variety of biomedical applications, including oral drug delivery, diagnostics, plasmonic resonance and photothermal ablation therapy. Preliminary results indicate the safety,…

Enhancing cannabinoids’ therapeutic efficacy In our previous technical note, we reported on the encapsulation of CBD vs CBDA (1). The work here-in continues on that theme in terms of studying the differences in encapsulating different…

Highlights • Microneedles are promising devices used for painless transdermal drug delivery. • Biological effects of therapeutic agents can be improved by tuning their release behavior. • Microneedles can be…

Herein, a nano-micelle drug delivery system was developed to orally improved zingerone’s bioavailability and its antitumor effect. Indeed, zingerone-loaded D-α-tocopheryl polyethylene glycol succinate micelles (ZTMs) were effectively…

Nanosized particles have appealing attributes, which have gotten impressive consideration in the last few decades. Polymeric nanoparticles (PNP)s are particles or particulate materials with size at least in the range of 10–100 nm in one…