Film coating is often considered to be a challenging step in tablet manufacturing. While the choice of film coating depends on factors like API’s characteristics, protective function, release profile of a drug and aesthetics of a tablet,…

Terahertz pulsed imaging (TPI) was introduced approximately fifteen years ago and has attracted a lot of interest in the pharmaceutical industry as a fast, non-destructive modality for quantifying film coatings on pharmaceutical dosage…

Barrier film coating is the most appropriate and widely used approach to protect solid dosages from moisture, particularly for water-sensitive drugs including herbal medicines. This study aims to produce the barrier film of a typical herbal…

This research aims to address a gap in our understanding of the mechanisms by which pharmaceutical tablets achieve highly reproducible and predictable drug release. The present industrial and regulatory practice is centred around tablet…

In the pharmaceutical industry, the systematic optimization of formulation using Quality by Design (QbD) approach is economic, highly precise and ensures product quality. The current endeavor was aimed to prepare escitalopram ultra-fast…

The effects of material stiffness, host and guest particle sizes, and mixing intensity on dry coating quality were investigated using a high-intensity vibrational mixer, using KCl, cornstarch, aluminum silicate and nano-sized silica. The…

The application of hot melt coating (HMC) as an economic and solvent-free technology is restricted in pharmaceutical development, due to the instable solid-state of HMC excipients resulting in drug release instability. We have previously…

Film coating of pharmaceutical dosage forms, such as tablets and pellets, can be used to tailor the drug release profile. With that regard, a uniform coating thickness of a single tablet (intra-tablet), all tablets (inter-tablet) and…

Advantages of Hot Melt Coating (HMC) One advantage for the pharmaceutical industry is the simplification of complex dosage schemes, as several active ingredients can be combined, even those that cannot normally be combined. As the…

Guidance for an excellent Hot Melt Coating Part 2 in the series of 3 articles In order to reduce the problems of other solvent-based coating processes, such as time and cost intensity, the active ingredient coating by means of Hot Melt…