Lubrizol
Lubrizol Life Science Health (LLS Health) specializes in pharmaceutical partnership and helping clients from idea to execution by providing best-in-class excipients for pharmaceutical and over-the-counter products. When you partner with…
Comparison of Different Liquid and Semisolid Vehicles Selected for Oral Administration of Pellets…
The acceptability and palatability of a dosage form are extremely important to improve patient compliance. Mixing oral solid dosage forms with food carriers is often necessary to ease swallowing and provide the taste-masking effect. The…
Optimized flurbiprofen sustained-release matrix pellets prepared by extrusion/spheronization
Flurbiprofen (FBP) is an ibuprofen derivative with less gastric side effects and short biological half-life (4.7–5.7 h). The study aimed to formulate FBP as a sustained-release pellets by extrusion/spheronization to overcome its short…
In-Depth Study into Polymeric Materials in Low-Density Gastroretentive Formulations
The extensive use of oral dosage forms for the treatment of diseases may be linked to deficient pharmacokinetic properties. In some cases the drug is barely soluble; in others, the rapid transit of the formulation through the…
Mucoadhesive bilayered buccal platform for antifungal drug delivery into the oral cavity
A drug delivery technology comprising a mucoadhesive bilayered buccally anchored tablet containing natamycin was developed. The concept was to anchor the tablet to the buccal tissue and allow controlled release of the drug through the…
Nanostructured lipid carriers loaded with Halobetasol propionate for topical treatment of…
The aim of this research was the development and characterization of three gel dosage forms of Halobetasol propionate loaded lipid nanoparticles (HB-NLC) for the treatment of inflammatory skin diseases. A Pluronic gel (Pl-HB-NLC), a…
DC Excipients – A list of excipients for direct compression
Direct compression (DC) the fastest and most economic way to manufacture a tablet as it directly goes from powder mixing to tableting without any further production steps. It plays a key role in continuous manufacturing thanks to the high…
Characterization of ternary amorphous solid dispersion containing hypromellose phthalate and…
Hot melt extrusion is a promising technology for producing amorphous solid dispersions, however, there is a risk of thermal degradation or residual crystallinity formation. This caveat may be addressed by optimizing formulations and…
Formulation, optimization and in vitro evaluation of nanostructured lipid carriers for topical…
This work was aimed to formulate topical Apremilast loaded nanostructured lipid-carriers (NLCs) for the management of psoriasis.
Psoriasis is a widespread skin condition considered to be a Th1 autoimmune skin disease and characterized by…
Formulation, optimization and in vitro evaluation of nanostructured lipid carriers for topical…
This work was aimed to formulate topical Apremilast loaded nanostructured lipid-carriers (NLCs) for the management of psoriasis.
Psoriasis is a widespread skin condition considered to be a Th1 autoimmune skin disease and characterized by…