Loratadine (LRD) belongs to second-generation tricyclic H1 antihistamine class, known for its non-sedating properties in allergic reactions. H1 antihistamines avoid and block the responses to allergens or histamine in nose and…

Oral administration is the most commonly used form of treatment due to its advantages, including high patient compliance, convenient administration, and minimal preparation required. However, the traditional preparation process of oral…

The manufacture of medicines on demand for a particular patient, at the point of care, may be achieved via 3D printing, improving therapeutic outcomes, medication adherence and patient safety. Tablets are often printed using a combination…

Introduction Cannabidiol (CBD) is a promising non-psychoactive cannabinoid that shows several clinical outcomes. Commercially, this molecule is used in Epidiolex® (Greenwich Biosciences, Inc), a Food and Drug Administration…

The low bioavailability and side effects of conventional drugs for eye disease necessitate the development of efficient drug delivery systems. Accompanying the developments of nanofabrication techniques, nanomaterials have been recognized…

The in-situ formation of nanoparticles from polymer-based solid medicines, although previously described, has been overlooked despite its potential to interfere with oral drug bioavailability. Such polymeric pharmaceuticals are becoming…

Additive manufacturing (AM) is an emerging pharmaceutical manufacturing technique feasible for patient-centric personalised medicine with tailored pharmacotherapy. Fused filament fabrication (FFF) is a highly emphasised 3D printing…

Since the emergence of Soluplus® (SOL) as a commercial graft copolymer, multiple publications have been issued on its promising potential as a solubilizing excipient that could promote the dissolution rate and bioavailability of several…

Hot-melt extrusion (HME) and subsequent FDM 3D printing offer great potential opportunities in the formulation development and production of customized oral dosage forms with poorly soluble drugs. However, thermal stress within these…

The pharmaceutical industry needs innovative, new and novel excipients solutions to support the developments in next generation therapeutics, new manufacturing concepts (eg. continuous manufacturing, 3Dprinting, etc.), drug delivery and API…