Many active pharmaceutical ingredients have poor water-solubility and/or low permeability, leading to bioavailability issues. Lipid-based formulation (LBF) is a well-known strategy to overcome these hurdles and increase in vivo drug…

Spray drying is a constructive single-step manufacturing technique used to produce dry powder. Spray drying plays a remarkable role in producing inhalable powder formulations due to its ability to engineer particles with optimized…

Obtaining solubility data in a sufficiently broad range of lipid excipients is the first step towards the development of a lipid-based formulation. Solubility is an indication of expected drug load and performance of the formulation.…

Pediatric formulations are strongly demanded from healthcare professionals and caregivers. Currently, solid dosage forms have been studied as pediatric preparations. In this article, we report the development of orally disintegrating…

Stimulated by Pharma 4.0, the pharmaceutical industry is changing from batch-wise to continuous manufacturing. Therefore, individual processing steps such as blending of the active pharmaceutical ingredient (API) with excipients have to be…

What is the ExciPerience? ExciPerience 2021 was the new virtual event around every aspect of pharmaceutical excipients. ExciPerience covered all areas from basic or advanced research and formulation to manufacturing and regulatory. It…

Palatability and patient acceptability are critical attributes of dispersible tablet formulation. Co-processed excipients could provide improved organoleptic profile due to rational choice of excipients and manufacturing techniques. The aim…

Co-processed excipients may enhance functionality and reduce drawbacks of traditional excipients for the manufacture of tablets on a commercial scale. The following study aimed to characterise a range of co-processed excipients that may…

This article aims to compare three commercially available co-processed excipients (CPEs), namely the F-Melts® type C,M and F1. All three CPEs were subjected to the evaluation of their physical properties and afterwards compacts were…

Pharmaceutical excipient development is an extensive process requiring a series of pre-formulation studies to evaluate their performance. The present study compares the conventional compaction and compression pre-formulation studies with…