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Stability of Free and Liposomal Encapsulated RNA on a Mucoadhesive PVA Polymer for Esophageal RNA…

Jul 12, 2024

Abstract The development of RNA and oligonucleotide-based therapeutics is a longstanding goal and is currently gaining significant attention. Several RNA-based drugs are approved for clinical use. Others are under investigation or in…

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A review of hot melt extrusion technology: Advantages, applications, key factors and future…

Jun 27, 2024

Abstract After decades of development, hot melt extrusion (HME) technology has matured as a well-established pharmaceutical methodology. Through the process of extruding both drug and carrier materials in a molten state under specific…

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Formulation and evaluation of ivermectin-loaded dissolving microarray patches for rosacea disease

Jun 13, 2024

Abstract Purpose This investigation aims to develop and characterise dissolving microarray patches (MAPs) loaded with ivermectin (IVM) for rosacea therapy. Methods Tween® 80 and Soluplus® were evaluated to enhance the water solubility…

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Novel nano-in-micro fabrication technique of diclofenac nanoparticles loaded microneedle patches for…

Jun 4, 2024

Abstract Diclofenac, a nonsteroidal anti-inflammatory drug, is commonly prescribed for managing osteoarthritis, rheumatoid arthritis, and post-surgical pain. However, oral administration of diclofenac often leads to adverse effects. This…

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Nanostructured Lipid Carriers for Oral Treatment of Leishmaniasis: Design and Preclinical Evaluation

May 15, 2024

Pentavalent antimonials are the primary treatment for leishmaniasis due to their proven efficacy and cost-effectiveness. However, they present poor oral absorption, parenteral administration, and serious adverse effects due to prolonged…

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Lipid-based nanoparticles as a promising treatment for the skin cancer

May 9, 2024

Abstract The prevalence of skin disorders, especially cancer, is increasing worldwide. Several factors are involved in causing skin cancer, but ultraviolet (UV) light, including sunlight and tanning beds, are considered the leading…

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Kollidon® 90 Evo – A highly effective water soluble binder with low impurity profile

May 9, 2024

Join the evolution of the BASF PVP portfolio! Kollidon® 90 Evo combines outstanding purity and innovative packaging. Kollidon® 90 Evo is a highly effective binder with exceptional purity Very low impurity profile, e.g.,…

Sorbitol as Pharmaceutical Excipient

Apr 25, 2024

Sorbitol, a polyol also known as glucitol, plays a significant role in the pharmaceutical industry as a versatile excipient and active pharmaceutical ingredient (API). This sugar alcohol is widely utilized for its unique properties, serving…

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Polymeric microspheres redefining the landscape of colon-targeted delivery: A contemporary update

Apr 25, 2024

Abstract During recent times, the delivery of the medications to the colon has seen more interest by the researchers, as it proved to be providing both options for treating local colon-related conditions and a route for systemic delivery…

PBP World Meeting 2024 Posters

Apr 10, 2024

The PBP World Meeting 2024 took place on March 18 - 21 in Vienna. On this page you can find a selection of posters that were exhibited at the World meeting 2024. Take the chance and read through the posters! Contact: Florian Engelsing…

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