Kollicoat® Smartseal (Methyl methacrylate and diethylaminoethyl methacrylate copolymer dispersion) which is used for taste masking and moisture protection, has shown the ability for forming solid dispersion. The present study aimed to check…

Veklury™ by Gilead Sciences, Inc., containing antiviral drug, remdesivir (REM) has received emergency authorization in the USA and in Europe for COVID-19 therapy. Here, for the first time, we describe details of the non-covalent, host-guest…

Several strategies have been explored to obtain effective econazole nitrate (ECN) concentrations at the site of application for a prolonged time. In this paper, different gelatin-based film formulations for vaginal application were…

7 October 2020 & 13 October 2020 – both 12:00 PM EST, 9:00 AM PST Using Speciality Excipients from Fuji Chemical Industries to Develop High Quality Medicine. Join Fuji in their upcoming Webinar on how to solve your…

Solid dispersions – a great way to increase the solubility and bioavailability of your drug In a solid dispersion the drug is dispersed in a carrier with the system appearing to be in a solid state. Target is an increase in solubility and…

"Hot melt extrusion (HME), a manufacturing technique traditionally used in the plastic and food industries, is now attracting significant interest from the pharmaceutical manufacturing sector. This is primarily because HME…

Highlights • Solubility enhancement of Apremilast using Hot melt extrusion technology via Corotating Twin Screw Extruder. • Theoretical and experimental determination of drug-polymer miscibility. • Influence of Extruder…

AFFINISOL™ hydroxypropyl methylcellulose (HPMC) is a water-soluble cellulosic polymer that can help optimize solubility enhancement by maintaining stable solid dispersions and inhibiting API crystallization. More sophisticated drug…

In drug development here is no one-size-fits-all approach which can be applied to allactive pharmaceutical ingredients (APIs). The best formulations and solutions depend on many characteristics, including the API characteristics, route of…