Cyclodextrins (CDs) are cyclic oligosaccharides that emerged as industrial excipients in the early 1970s and are currently found in at least 130 marketed pharmaceutical products, in addition to numerous other consumer products. Although CDs…

Orodispersible drug formulations are a current trend in the pharmaceutical industry, mostly intended for pediatric and geriatric patients. Oral lyophilizates are solid forms, intended either to be placed in the mouth or to be dispersed (or…

Nowadays, a high number of pipeline drugs are poorly soluble and require solubility enhancement by e.g., manufacturing of amorphous solid dispersion. Pharmaceutical 3D printing has great potential in producing amorphous solid oral dosage…

Poster presented at 4th European Conference on Pharmaceutics 20-21 March 2023 | Marseille, France: Drug loaded pellets were produced by using the ProCell® lab system technology. The aim was to produce highly drug loaded matrix pellets…

Introduction Controlled release dosage forms deliver an effective dose of the active pharmaceutical ingredient over a prolonged duration, which is particularly advantageous to maintain a constant plasma drug concentration within the…

We all know that medicines are often tablets and capsules right? But what are they, how do they work and how are they made? In this video PharmaDrama aka Prof. Simon Gaisford looks at the formulation of hard-shell pharmaceutical capsules.…

Tablets are the most common pharmaceutical dosage form - but why, and what are they? In this video PharmaDrama aka Prof. Simon Gaisford discusses what tablets are, what they contain, how they are made and how you should take them. He also…

SEE PEARLITOL® CR-H Roquette´s new, industry-first mannitol and hydroxypropyl methylcellulose (HPMC) blend, designed for controlled release drug formulation. Leave behind wet granulation, lengthy drying times and limited flowability…

High shear wet granulation and tableting (HSWG-T) are complex pharmaceutical processes, which makes tablet quality be influenced by many variables including raw material attributes, process variables, and intermediate granule properties. To…

3D printing technologies enable medicine customization adapted to patients’ needs. There are several 3D printing techniques available, but majority of dosage forms and medical devices are printed using nozzle-based extrusion, laser-writing…