Abstract The 3–dimensional printing process (3DP) was patented in the 1980s, but the utilization of this process has expanded substantially over the past decade, to which the pharmaceutical industry is a major contributor. With increasing…

Abstract Although probiotics are mostly administered in the form of capsules, there are some advantages of tablets in terms of production effort, cost efficiency and stability of the probiotic bacteria. As probiotics are sensitive to high…

Abstract Compounded tablets are solid dosage forms that contain active pharmaceutical ingredients that are usually formulated with suitable pharmaceutical excipients. Fillers are inert ingredients used as bulking agents that can affect the…

Abstract Due to their large potential applications in human diseases such as gastrointestinal disorders, immunomodulation or cholesterol reduction, probiotic products are of great interest to the pharmaceutical industry. The formulation…

Digital twins capacitate the industry 4.0 paradigm by predicting and optimizing the performance of physical assets of interest, mirroring a realistic in-silico representation of their functional behaviour. Although advanced digital twins…

PHARMATRANS SANAQ offers excipients and active ingredients of outstanding quality and performance. With our research & development skill and tradition, we commit to study innovative technological solutions providing excipients…

Many orally dosed APIs are bioavailable only when formulated as an enteric dosage form to protect them from the harsh environment of the stomach. However, an enteric formulation is often accompanied with a higher development effort in the…

Carbamazepine is a medicine used to manage epilepsy and partial or tonic-clonic seizures. This study aimed at formulating and obtaining carbamazepine orodispersible tablets for paediatric use at a 50 mg dose, with a diameter not greater…

Addition of pharmaceutical excipients is a commonly used approach to decrease the viscosity of highly concentrated protein formulations, which otherwise could not be subcutaneously injected or processed. The variety of protein–protein…

Objective The aim of this study was to use an alternative granulation technique, solventless roll compaction, and to investigate the effect of the roll compaction pressure on the properties of granules and high-drug-loaded (80%, w/w)…