Liposomes, nanoemulsions and polymeric nanoparticles have all shown promise in improving the therapeutic benefits of cannabinoids, but the full potential of these therapies has not yet been unlocked. Nanotechnology for active pharmaceutical…

Encapsulation technologies can be used to preserve therapeutic and bioactive compounds from harsh conditions (e.g., light, moisture, and oxygen) and biological destruction (enzymes, metabolism, and phagocytosis). Encapsulation involves the…

pharma's almanac - September 29, 2020 PAP-Q3-20-CL-024 - Shiksha Mantri, Ph.D. - Adela Kasselkus, Ph.D. Lipid-based drug delivery systems offer several advantages, including improving the stability, solubility, bioavailability, and…

Plant-derived phenolic compounds have multiple positive health effects for humans attributed to their antioxidative, anti-inflammatory, and antitumor properties, etc. These effects strongly depend on their bioavailability in the organism.…

The role of vaccine adjuvants in the immune response Vaccine adjuvants (from the Latin adjuvare meaning “to help”) are substances that increase the intensity of the immune response after co-administration with an antigen. They are…

This work introduces VaxiPatch, a novel vaccination system comprised of subunit glycoprotein vaccine antigens, adjuvants and dermal delivery. For this study, rHA of influenza virus B/Colorado/06/2017 was incorporated into synthetic…

Many drug molecules that are currently in the market suffer from short half-life, poor absorption, low specificity, rapid degradation, and resistance development. The design and development of lipophilic prodrugs can provide numerous…

Drug delivery technology has a wide spectrum, which is continuously being upgraded at a stupendous speed. Different fabricated nanoparticles and drugs possessing low solubility and poor pharmacokinetic profiles are the two major substances…

The eye is susceptible to various diseases commonly difficult to treat. To overcome the barriers imposed by this organ for required drugs penetration, technological strategies have been implemented to ocular formulations. Among them are the…