With the advent of continuous manufacturing, twin-screw melt granulation has attracted interest in the pharmaceutical industry as a method for co-processing excipients and developing new formulations. Twin-screw melt granulation relies on…

Abstract Although probiotics are mostly administered in the form of capsules, there are some advantages of tablets in terms of production effort, cost efficiency and stability of the probiotic bacteria. As probiotics are sensitive to high…

Abstract Compounded tablets are solid dosage forms that contain active pharmaceutical ingredients that are usually formulated with suitable pharmaceutical excipients. Fillers are inert ingredients used as bulking agents that can affect the…

CPHI worldwide opens its doors again. This year in Frankfurt at the Messe Frankfurt. In two weeks, from 1st to 3rd November, you can finally have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack, P-MEC, FDF, ICSE…

A week ago I wrote about the importance of new and novel excipients for the pharmaceutical industry and presented Klucel™ xtend and BioSustane™ in last week´s edition of "The Excipients Week". In the meantime I launched a small poll with…

Abstract Due to their large potential applications in human diseases such as gastrointestinal disorders, immunomodulation or cholesterol reduction, probiotic products are of great interest to the pharmaceutical industry. The formulation…

Many orally administrated drugs exhibit poor bioavailability due to their limited solubility. The smartFilm technology is an innovative approach to improve the drug aqueous solubility, where the drug is embedded within the matrix of…

PHARMATRANS SANAQ offers excipients and active ingredients of outstanding quality and performance. With our research & development skill and tradition, we commit to study innovative technological solutions providing excipients…

Additive manufacturing has a wide range of applications and has opened up new methods of drug formulation, in turn achieving attention in medicine. We prepared styrene–isobutylene–styrene triblock copolymers (SIBS; Mn = 10 kDa–25 kDa, PDI…

Objective The aim of this study was to use an alternative granulation technique, solventless roll compaction, and to investigate the effect of the roll compaction pressure on the properties of granules and high-drug-loaded (80%, w/w)…