Nowadays, fluidized bed granulation is a widely used technique in the pharmaceutical industry. Several factors, including process settings, powder qualities, and binder properties, impact its performance. The monitoring of the fluidized bed…

3D printing of pediatric-centered drug formulations can provide suitable alternatives to current treatment options, though further research is still warranted for successful clinical implementation of these innovative drug products.…

Given the benefits of high printing precision and capability, the selective laser sintering technique has been used to manufacture medicines and implants with unique engineering and functional properties. Using homogenized beams with a…

This study was aimed to utilize the Moisture Activated Dry Granulation (MADG) technique to formulate Bicalutamide tablet and identify critical factors influencing its dissolution. The Bicalutamide inclusion complex was formed using the…

In the present study, the performance of PROSOLV® EASYt ab SP was tested in four DC formulations with different model APIs. Each of the selected APIs presented a particular challenge in terms of producing tablets with suitable hardness,…

In situ calcium pectinate-coated pellets were proposed by applying an alternate coating method to drug-layered pellets to achieve colon-specific drug delivery. Solution layering of metroprolol tartrate, a water-soluble model drug, on inert…

Sodium starch glycolate (SSG) is most widely used excipient in the field of pharmaceutical sciences. SSG is extensively used as a superdisintegrant in different drug formulations. This review article aims to discuss chemistry, synthesis,…

The 12th APV PBP World Meeting took place from 28 – 31 March 2022 in Rotterdam. There was a poster section at the event where really interesting scientific posters were presented. Therefore we asked the presenting scientists if we could…

Moisture is a crucial quality property for granules in fluidized bed granulation (FBG) and accurate prediction of the granule moisture is significant for decision making. This study proposed a novel stacking ensemble method to predict the…